光响应型喹啉连接荧光碳点用于可控抗癌药物递送。
Photoresponsive quinoline tethered fluorescent carbon dots for regulated anticancer drug delivery.
机构信息
Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur-721302, India.
出版信息
Chem Commun (Camb). 2013 Nov 18;49(89):10471-3. doi: 10.1039/c3cc46078a.
PMID:24080791
Abstract
A photoresponsive nano drug delivery system (DDS) was constructed using two new ingredients: fluorescent carbon dots and a quinoline based phototrigger. The strong fluorescent properties of carbon dots have been explored for in vitro cellular imaging application, and the phototrigger ability of quinoline was exploited for efficient anticancer drug release using both one-photon and two-photon excitation.
摘要
构建了一种光响应纳米药物输送系统 (DDS)，使用了两种新成分：荧光碳点和基于喹啉的光触发剂。碳点的强荧光特性已被探索用于体外细胞成像应用，而喹啉的光触发能力则被用于利用单光子和双光子激发实现高效抗癌药物释放。
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