Korf Dirk J, Nabben Ton, Benschop Annemieke, Ribbink Kim, van Amsterdam Jan G C
Bonger Institute of Criminology, University of Amsterdam, Amsterdam, The Netherlands.
Eur Addict Res. 2014;20(2):66-74. doi: 10.1159/000353237. Epub 2013 Sep 27.
The aim of this study was to identify in recreational drug users the factors which increase the risk of overdosing (OD) with γ-hydroxybutyrate (GHB). A purposive sample of 45 experienced GHB users was interviewed, equally divided into three groups (never OD, occasional OD, and repeat OD). The repeat OD group scored highest on many risk factors regarding GHB use, the occasional OD group scored intermediate, and the never OD group scored lowest. Participants, whether or not they had overdosed on GHB, most often perceived GHB use (e.g. using more GHB than usual, using GHB doses too closely together) as the main reason for GHB OD, and many participants who had overdosed on GHB reported that they had taken more GHB than usual at their most recent occasion of GHB OD. No significant differences in co-use of GHB with other substances were found between the three groups. Our findings indicate that using GHB in the company of groups of friends probably reduces, but does not eliminate, the risk of OD.
本研究的目的是在娱乐性药物使用者中确定增加γ-羟基丁酸(GHB)过量用药(OD)风险的因素。对45名有经验的GHB使用者进行了一项有目的抽样访谈,将他们平均分为三组(从未过量用药、偶尔过量用药和反复过量用药)。在许多与使用GHB相关的风险因素方面,反复过量用药组得分最高,偶尔过量用药组得分中等,从未过量用药组得分最低。参与者无论是否有过GHB过量用药经历,大多认为使用GHB(例如,使用比平常更多的GHB、使用GHB的剂量间隔过短)是GHB过量用药的主要原因,许多有过GHB过量用药经历的参与者报告称,在他们最近一次GHB过量用药时,他们服用的GHB比平常更多。三组之间在GHB与其他物质联合使用方面未发现显著差异。我们的研究结果表明,在朋友群体中使用GHB可能会降低但不会消除过量用药的风险。