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透析:含低葡萄糖的腹膜透析液:好还是坏?

Dialysis: low-glucose-containing peritoneal dialysis solutions: good or bad?

机构信息

George Institute for Global Health, Splendor Forum, Jasola, New Delhi, India.

出版信息

Nat Rev Nephrol. 2013 Nov;9(11):635-6. doi: 10.1038/nrneph.2013.205. Epub 2013 Oct 1.

DOI:10.1038/nrneph.2013.205
PMID:24080795
Abstract

Two trials of low-glucose-containing peritoneal dialysis regimen in patients with diabetes mellitus show that although this strategy improved glycaemic control, it was associated with increased risk of serious adverse events and mortality. These studies suggest caution is needed when evaluating effectiveness using surrogate measures and awareness of confounding factors is important.

摘要

两项针对糖尿病患者的低葡萄糖含量腹膜透析方案的试验表明,尽管这种策略改善了血糖控制,但与严重不良事件和死亡率增加有关。这些研究表明,在使用替代指标评估疗效时需要谨慎,并且认识混杂因素很重要。

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Dialysis: low-glucose-containing peritoneal dialysis solutions: good or bad?透析:含低葡萄糖的腹膜透析液:好还是坏?
Nat Rev Nephrol. 2013 Nov;9(11):635-6. doi: 10.1038/nrneph.2013.205. Epub 2013 Oct 1.
2
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本文引用的文献

1
Randomized, controlled trial of glucose-sparing peritoneal dialysis in diabetic patients.随机对照试验研究葡萄糖保存型腹膜透析在糖尿病患者中的应用。
J Am Soc Nephrol. 2013 Nov;24(11):1889-900. doi: 10.1681/ASN.2012100987. Epub 2013 Aug 15.
2
The impact of dialysis modality on quality of life: a systematic review.透析方式对生活质量的影响:一项系统综述。
J Ren Care. 2011 Dec;37(4):190-200. doi: 10.1111/j.1755-6686.2011.00244.x.
3
Glycemic control and survival in peritoneal dialysis patients with diabetes mellitus.糖尿病腹膜透析患者的血糖控制与生存。
Clin J Am Soc Nephrol. 2011 May;6(5):1041-8. doi: 10.2215/CJN.08921010. Epub 2011 Apr 21.
4
Glycated hemoglobin predicts mortality in nondiabetic patients receiving chronic peritoneal dialysis.糖化血红蛋白可预测接受慢性腹膜透析的非糖尿病患者的死亡率。
Am J Nephrol. 2010;32(6):567-74. doi: 10.1159/000321899. Epub 2010 Nov 10.
5
Mortality and technique failure in peritoneal dialysis patients using advanced peritoneal dialysis solutions.使用先进腹膜透析液的腹膜透析患者的死亡率和技术失败率
Am J Kidney Dis. 2009 Oct;54(4):711-20. doi: 10.1053/j.ajkd.2009.05.014. Epub 2009 Jul 19.
6
Icodextrin improves metabolic and fluid management in high and high-average transport diabetic patients.艾考糊精可改善高转运型及高平均转运型糖尿病患者的代谢及液体管理。
Perit Dial Int. 2009 Jul-Aug;29(4):422-32.
7
Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection.在糖尿病血液透析患者中,糖化白蛋白比糖化血红蛋白值是更好的血糖指标:贫血和促红细胞生成素注射的影响。
J Am Soc Nephrol. 2007 Mar;18(3):896-903. doi: 10.1681/ASN.2006070772. Epub 2007 Jan 31.
8
Benefit of glucose-free dialysis solutions on glucose and lipid metabolism in peritoneal dialysis patients.无糖透析液对腹膜透析患者糖脂代谢的益处。
Blood Purif. 2005;23(4):303-10. doi: 10.1159/000086553. Epub 2005 Jun 23.
9
Metabolic consequences of peritoneal dialysis.腹膜透析的代谢后果
Semin Dial. 2004 Nov-Dec;17(6):498-504. doi: 10.1111/j.0894-0959.2004.17610.x.
10
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overload.艾考糊精作为腹膜透析难治性液体超负荷患者的挽救治疗方法。
BMC Nephrol. 2001 Dec 3;2:2. doi: 10.1186/1471-2369-2-2.