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慢性肾脏病:肾脏病的理想血压——越低越好。

Chronic kidney disease: optimal blood pressure for kidney disease-lower is not better.

机构信息

The University of Chicago Medicine, MC1027, Room P-328A, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

出版信息

Nat Rev Nephrol. 2013 Nov;9(11):634-5. doi: 10.1038/nrneph.2013.206. Epub 2013 Oct 1.

DOI:10.1038/nrneph.2013.206
PMID:24080799
Abstract

Current guidelines recommend lowering blood pressure (BP) in patients with chronic kidney disease and hypertension. However, a new study suggests that achieving ideal systolic BP targets at the expense of low diastolic BP <70 mmHg is not advantageous for outcomes.

摘要

目前的指南建议降低慢性肾脏病和高血压患者的血压。然而,一项新的研究表明,为了达到理想的收缩压目标而牺牲舒张压<70mmHg 并不有利于预后。

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Medicine (Baltimore). 2017 Jun;96(26):e7380. doi: 10.1097/MD.0000000000007380.
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Update on blood pressure goals in diabetes mellitus.糖尿病患者血压目标的最新进展。
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本文引用的文献

1
Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study.美国慢性肾脏病退伍军人的血压与死亡率:一项队列研究。
Ann Intern Med. 2013 Aug 20;159(4):233-42. doi: 10.7326/0003-4819-159-4-201308200-00004.
2
2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).2013年欧洲高血压学会(ESH)和欧洲心脏病学会(ESC)动脉高血压管理指南:欧洲高血压学会(ESH)和欧洲心脏病学会(ESC)动脉高血压管理特别工作组
J Hypertens. 2013 Jul;31(7):1281-357. doi: 10.1097/01.hjh.0000431740.32696.cc.
3
Summary of KDIGO guideline. What do we really know about management of blood pressure in patients with chronic kidney disease?
KDIGO 指南摘要。我们对慢性肾脏病患者血压管理的了解到底有多少?
Kidney Int. 2013 Mar;83(3):377-83. doi: 10.1038/ki.2012.425. Epub 2013 Jan 16.
4
Summary of revisions for the 2013 clinical practice recommendations.2013年临床实践建议修订摘要。
Diabetes Care. 2013 Jan;36 Suppl 1(Suppl 1):S3. doi: 10.2337/dc13-S003.
5
The j-point phenomenon in aggressive therapy of hypertension: new insights.高血压强化治疗中的 J 点现象:新的认识。
Curr Atheroscler Rep. 2012 Apr;14(2):124-9. doi: 10.1007/s11883-012-0233-4.
6
Blood pressure components and end-stage renal disease in persons with chronic kidney disease: the Kidney Early Evaluation Program (KEEP).慢性肾脏病患者的血压成分与终末期肾病:肾脏早期评估项目(KEEP)
Arch Intern Med. 2012 Jan 9;172(1):41-7. doi: 10.1001/archinternmed.2011.619.
7
Intensive blood-pressure control in hypertensive chronic kidney disease.高血压性慢性肾脏病的强化血压控制。
N Engl J Med. 2010 Sep 2;363(10):918-29. doi: 10.1056/NEJMoa0910975.
8
Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial.非糖尿病慢性肾病患者肾保护的血压控制(REIN-2):多中心随机对照试验
Lancet. 2005;365(9463):939-46. doi: 10.1016/S0140-6736(05)71082-5.
9
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.强化降压与小剂量阿司匹林对高血压患者的影响:高血压最佳治疗(HOT)随机试验的主要结果。HOT研究组
Lancet. 1998 Jun 13;351(9118):1755-62. doi: 10.1016/s0140-6736(98)04311-6.
10
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