Comenius University, Faculty of Mathematics, Physics and Informatics, Department of Experimental Physics, Mlynska dolina F2 842 48 Bratislava, Slovakia.
Analyst. 2013 Nov 21;138(22):6907-12. doi: 10.1039/c3an00964e.
We have developed a new type of corona discharge (CD) for atmospheric pressure chemical ionization (APCI) for application in ion mobility spectrometry (IMS) as well as in mass spectrometry (MS). While the other CD-APCI sources are able to generate H3O(+)·(H2O)n as the major reactant ions in N2 or in zero air, the present CD-APCI source has the ability to generate up to 84% NO(+)·(H2O)n reactant ions in zero air. The change of the working gas from zero air to N2 allows us to change the major reactant ions from NO(+)·(H2O)n to H3O(+)·(H2O)n. In this paper we present the description of the new CD-APCI and discuss the processes associated with the NO(+) formation. The selective formation of NO(+)·(H2O)n reactant ions offers chemical ionization based on these ions which can be of great advantage for some classes of chemicals. We demonstrate here a significant increase in the sensitivity of the IMS-MS instrument for monoaromatic volatile organic compound (VOC) detection upon NO(+)·(H2O)n chemical ionization.
我们开发了一种新型大气压放电（CD）用于大气压化学电离（APCI），应用于离子迁移谱（IMS）以及质谱（MS）。虽然其他 CD-APCI 源能够在 N2 或零气中生成 H3O(+)·(H2O)n 作为主要反应离子，但目前的 CD-APCI 源能够在零气中生成高达 84%的 NO(+)·(H2O)n 反应离子。将工作气体从零气改为 N2 可以使我们将主要反应离子从 NO(+)·(H2O)n 变为 H3O(+)·(H2O)n。本文介绍了新型 CD-APCI 的描述，并讨论了与 NO(+)形成相关的过程。NO(+)·(H2O)n 反应离子的选择性形成提供了基于这些离子的化学电离，这对某些类别的化学物质具有很大的优势。我们在这里证明，NO(+)·(H2O)n 化学电离可显著提高 IMS-MS 仪器对单芳香族挥发性有机化合物（VOC）检测的灵敏度。
