Beele Hilde, van Wijk Marja J, Parker Robert, Sánchez-Ibáňez Jacinto, Brubaker Scott A, Wulff Birgit, Richters Cornelia D, Cox Mike, Warwick Ruth M, Eastlund Ted
Tissue Bank, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium,
Cell Tissue Bank. 2013 Dec;14(4):561-70. doi: 10.1007/s10561-013-9400-2. Epub 2013 Oct 1.
The European Association of Tissue Banks (EATB) donor case workshop is a forum held within the program of the EATB annual congress. The workshop offers an opportunity to discuss and evaluate approaches taken to challenging situations regarding donor selection, it promotes consensus development in deciding tissue donor acceptability when donor health issues are not addressed in standards and regulations, and serves to strengthen the professional tissue banking networks across Europe and beyond. This report reflects some of the discussion at the workshop during the annual congress in Vienna in 2012. The cases presented dealt with problems encountered by tissue bank facilities concerning idiopathic thrombocytopenia and auto-immune disorders, hemodilution and blood sample identification, premalignant and malignant lesions, and Huntington's disease. The discussions during the workshop demonstrate that the implications on the safety of tissue transplantation of various tissue donor illnesses, physical findings and behaviours, and the preventive measures taken by tissue facilities, may not always be agreed by tissue facility medical directors and other professionals. Moreover, they reveal that operating procedures, regulations and standards cannot comprehensively cover all tissue donor findings, medical histories and circumstances surrounding the cause of death. For many of the issues raised, there is a need for scientific research to provide a better evidence base for future deliberations about the suitability and eligibility of tissue allograft donors.
欧洲组织库协会（EATB）供体案例研讨会是在EATB年度大会项目框架内举办的一个论坛。该研讨会提供了一个机会，用以讨论和评估在供体选择方面应对具有挑战性情况所采取的方法，促进在标准和法规未涉及供体健康问题时就组织供体可接受性达成共识，并有助于加强欧洲及其他地区的专业组织库网络。本报告反映了2012年在维也纳举行的年度大会期间该研讨会上的部分讨论内容。所展示的案例涉及组织库机构在特发性血小板减少症和自身免疫性疾病、血液稀释和血样识别、癌前病变和恶性病变以及亨廷顿舞蹈症方面遇到的问题。研讨会上的讨论表明，组织库机构的医学主任和其他专业人员对于各种组织供体疾病、身体检查结果和行为以及组织库机构所采取的预防措施对组织移植安全性的影响，可能并非总能达成一致。此外，这些讨论还表明，操作程序、法规和标准无法全面涵盖所有组织供体的检查结果、病史以及围绕死亡原因的具体情况。对于所提出的许多问题，需要开展科学研究，以便为未来关于组织同种异体移植供体的适用性和资格认定的审议提供更好的证据基础。
