Redhu Rakesh, Poonia Rajpal
Department of Surgery, Government Medical College and Hospital, Chandigarh, Punjab, India.
J Craniovertebr Junction Spine. 2012 Jul;3(2):67-9. doi: 10.4103/0974-8237.116542.
A 30-year-old female patient presented with complaints of backache, weakness in both lower limbs and bladder/bowel dysfunction. Imaging showed an osteolytic lesion at tenth dorsal (D10) vertebra with anterior compression on the spinal cord. Complete intralesional tumor excision with reconstruction was carried out using the anterolateral extrapleural approach. Histopathological examination was suggestive of giant cell tumor (GCT). Because of complete intralesional tumor excision and fear of post-radiation osteonecrosis of bone used for delayed bony union, a conservative approach was used, and radiation therapy was not given. After one year of follow-up patient is doing well without any recurrence of the tumor and is ambulant with support. GCT of dorsal vertebral body is an uncommon entity and total en bloc excision is difficult. Therefore, the treatment strategy is not well-defined. We discuss in brief about incidence, presentation and various treatment modalities available for spinal GCT.
一名30岁女性患者主诉背痛、双下肢无力及膀胱/肠道功能障碍。影像学检查显示第10胸椎（D10）有溶骨性病变，脊髓前方受压。采用胸外侧胸膜外入路进行了病灶内肿瘤完整切除及重建。组织病理学检查提示为骨巨细胞瘤（GCT）。由于病灶内肿瘤完整切除，且担心用于延迟骨愈合的骨发生放射后骨坏死，故采用保守方法，未给予放射治疗。随访一年，患者情况良好，肿瘤无复发，借助支撑物可行走。胸椎椎体骨巨细胞瘤是一种罕见疾病，整块切除困难。因此，治疗策略尚不明确。我们简要讨论一下脊柱骨巨细胞瘤的发病率、临床表现及可用的各种治疗方式。
