Kajimoto Madoka, Hasegawa Shunji, Nomura Sadahiro, Inoue Hirofumi, Matsushige Takeshi, Ichiyama Takashi
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Japan.
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Japan.
Brain Dev. 2014 Aug;36(7):637-40. doi: 10.1016/j.braindev.2013.09.004. Epub 2013 Sep 29.
The patient is a healthy 11-year-old girl with no history of trauma or hearing impairment. She developed pneumococcal meningitis three times, at ages 7, 10, and 11. Intracranial examination revealed, pore expansion and cerebrospinal fluid leakage in the right internal acoustic foramen, which were attributed to a bone malformation of the base of the skull. A procedure was performed to close the cerebrospinal fluid leakage; no relapse has been observed thus far. Previous case reports indicate that repetitive bacterial meningitis is often caused by internal ear malformation, trauma, tumors, or surgical operation. This case suggests the possibility that underlying disorders may not be apparent in cases of repetitive bacterial meningitis and, more proactive investigations are required to prevent further recurrence of meningitis.
该患者是一名11岁健康女孩,无创伤史或听力障碍史。她在7岁、10岁和11岁时三次患肺炎球菌性脑膜炎。颅内检查发现右侧内耳道孔扩大及脑脊液漏,归因于颅底骨畸形。进行了封闭脑脊液漏的手术;迄今为止未观察到复发。既往病例报告表明,复发性细菌性脑膜炎常由内耳畸形、创伤、肿瘤或手术引起。本病例提示,在复发性细菌性脑膜炎病例中,潜在疾病可能并不明显,需要更积极的检查以预防脑膜炎进一步复发。