弗雷明汉心脏研究与心血管疾病的流行病学：历史视角。
The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective.
机构信息
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA; Population Research Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
出版信息
Lancet. 2014 Mar 15;383(9921):999-1008. doi: 10.1016/S0140-6736(13)61752-3. Epub 2013 Sep 29.
Abstract
On Sept 29, 2013, the Framingham Heart Study will celebrate 65 years since the examination of the first volunteer in 1948. During this period, the study has provided substantial insight into the epidemiology and risk factors of cardiovascular disease. The origins of the study are closely linked to the cardiovascular health of President Franklin D Roosevelt and his premature death from hypertensive heart disease and stroke in 1945. In this Review we describe the events leading to the foundation of the Framingham Heart Study, and provide a brief historical overview of selected contributions from the study.
摘要
2013 年 9 月 29 日，弗雷明汉心脏研究将迎来自 1948 年对第一名志愿者进行检查以来的 65 周年。在此期间，该研究深入了解了心血管疾病的流行病学和危险因素。该研究的起源与富兰克林·德拉诺·罗斯福总统的心血管健康及其 1945 年因高血压性心脏病和中风而过早去世密切相关。在这篇综述中，我们描述了导致弗雷明汉心脏研究成立的事件，并简要回顾了该研究的一些重要贡献。
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本文引用的文献
1
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2
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Circulation. 2013 Jan 1;127(1):e6-e245. doi: 10.1161/CIR.0b013e31828124ad. Epub 2012 Dec 12.
3
"A change of heart: how the people of framingham, massachusetts, helped unravel the mysteries of cardiovascular disease".
Discov Med. 2005 Feb;5(25):104-11.
4
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
Nat Genet. 2009 Aug;41(8):879-81. doi: 10.1038/ng.416. Epub 2009 Jul 13.
5
SIR JAMES MACKENZIE'S HEART.
Br Heart J. 1939 Jul;1(3):237-48. doi: 10.1136/hrt.1.3.237.
6
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination.
Am J Epidemiol. 2007 Jun 1;165(11):1328-35. doi: 10.1093/aje/kwm021. Epub 2007 Mar 19.
7
Profiling risk: the emergence of coronary heart disease epidemiology in the United States (1947-70).
Int J Epidemiol. 2006 Jun;35(3):720-30. doi: 10.1093/ije/dyl014. Epub 2006 Feb 15.
8
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society.
Circulation. 2005 Sep 20;112(12):e154-235. doi: 10.1161/CIRCULATIONAHA.105.167586. Epub 2005 Sep 13.
9
Ancel Keys.
Lancet. 2004;364(9452):2174. doi: 10.1016/S0140-6736(04)17578-8.
10
Obesity and the risk of new-onset atrial fibrillation.
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