Magyar D M, Hayes M F, Spirtos N J, Hull M E, Moghissi K S
Am J Obstet Gynecol. 1985 May 15;152(2):198-204. doi: 10.1016/s0002-9378(85)80022-3.
The routine use of intraperitoneal 32% dextran 70 has been suggested as an adjuvant to prevent postsurgical pelvic adhesions. Two hundred thirty-four women received an antiadhesion regimen consisting of intraperitoneal 32% dextran 70, dexamethasone, and promethazine. Ten women (4%) experienced spontaneous leakage of the dextran-peritoneal fluid mixture through their abdominal incisions. Painless bilateral swelling of the labia was noted in 18 women (8%). Mild abdominal bloating and weight gain of from 2.5 to 11 pounds were common. No anaphylactic reactions, peritonitis, or wound infections were experienced by any woman. Intraperitoneal dextran 70 appears to be a safe, well-tolerated antiadhesion adjuvant for routine use in gynecologic operations.
有人建议常规使用32%的腹腔内右旋糖酐70作为预防术后盆腔粘连的辅助药物。234名女性接受了由腹腔内32%右旋糖酐70、地塞米松和异丙嗪组成的抗粘连方案。10名女性（4%）出现右旋糖酐 - 腹腔液混合物通过腹部切口自发渗漏。18名女性（8%）出现无痛性双侧阴唇肿胀。轻度腹部胀气和体重增加2.5至11磅很常见。所有女性均未出现过敏反应、腹膜炎或伤口感染。腹腔内右旋糖酐70似乎是一种安全、耐受性良好的抗粘连辅助药物，可常规用于妇科手术。
