Basaldella Luca, Fiorindi Alessandro, Sammartino Francesco, De Caro Raffaele, Longatti Pierluigi
Department of Neurosurgery, Treviso Regional Hospital, University of Padova, Pzza. le Ospedale Civile 1, 31100, Treviso, Italy,
Childs Nerv Syst. 2014 Apr;30(4):607-11. doi: 10.1007/s00381-013-2289-z. Epub 2013 Oct 2.
Endoscopic third ventriculostomy is an established method for treating hydrocephalus. The third ventriculostomy site is considered a safe area that can be disrupted during surgical endoscopic procedures. The question of the clinical consequences of an apparently unavoidable injury to the floor of the third ventricle has been sporadically addressed in the literature. The aim of this study is to describe our anatomical and operative findings during endoscopic procedures performed in fluorescent mode after intravenous fluorescein injection and address the possible role of fluorescein-enhanced visualization of the median eminence as an accessory tool in order to partially spare this functional structure when performing ventriculostomy.
We prospectively administered intravenously 500 mg of fluorescein sodium in 12 consecutive endoscopic surgery cases. A flexible scope equipped with dual observation modes for both white light and fluorescence was used. Taking into account the position of the basilar apex and the need for a conveniently sized stoma, a perforation area was chosen and dilated using a Fogarty balloon, guided by fluorescein-enhanced visualization of the median eminence.
After a mean of 20 s in the fluorescent mode, the fluorescein enhanced the visualization of the median eminence-tuber cinereum complex. In our preliminary experience, by opening the stoma in the fluorescence mode, almost half of the visible median eminence surface can be spared from iatrogenic sacrifice.
Tailoring fluorescence-guided ventriculostomy is a feasible way of trying to preserve the median eminence and may have implications for the site and safety of this common surgical procedure.
内镜下第三脑室造瘘术是治疗脑积水的一种成熟方法。第三脑室造瘘部位被认为是手术内镜操作过程中可被破坏的安全区域。文献中偶尔会探讨第三脑室底部明显不可避免的损伤所带来的临床后果问题。本研究的目的是描述在静脉注射荧光素后以荧光模式进行内镜手术过程中的解剖学和手术发现,并探讨荧光素增强视交叉上核可视化作为辅助工具在进行脑室造瘘时部分保留该功能结构的可能作用。
我们对连续12例内镜手术病例前瞻性地静脉注射500mg荧光素钠。使用配备白光和荧光双观察模式的软性内镜。考虑到基底动脉尖的位置和造瘘口大小适宜的需要,在荧光素增强视交叉上核可视化的引导下,选择一个穿孔区域并用Fogarty球囊进行扩张。
在荧光模式下平均20秒后,荧光素增强了视交叉上核 - 灰结节复合体的可视化。根据我们的初步经验,在荧光模式下打开造瘘口,几乎一半可见的视交叉上核表面可避免医源性损伤。
定制荧光引导下的脑室造瘘术是试图保留视交叉上核的一种可行方法,可能会对这种常见手术的部位和安全性产生影响。