Tkaczewski Konrad, Dziuk Mirosław, Kocki Janusz, Pińkowski Roman
Klinika Kardiologii i Chorób Wewnętrznych Wojskowego Instytutu Medycznego w Warszawie.
Postepy Hig Med Dosw (Online). 2013 Sep 10;67:933-7. doi: 10.5604/17322693.1066058.
Coronary angiography and measurement of fractional flow reserve (FFR) are used for anatomical and functional assessment of coronary stenoses. The achievement of maximal coronary hyperaemia is crucial for an accurate calculation of FFR. Although adenosine and papaverine have been well validated, their mechanisms of action as well as methods of administration have some limitations. New and better agents to induce hyperaemia are therefore still being sought. Currently regadenoson, a selective adenosine A2A receptor agonist, seems to possess the characteristics of the almost ‹ideal› hyperaemic stimulus.
冠状动脉造影和血流储备分数（FFR）测量用于冠状动脉狭窄的解剖学和功能评估。实现最大冠状动脉充血对于准确计算FFR至关重要。尽管腺苷和罂粟碱已得到充分验证，但其作用机制以及给药方法存在一些局限性。因此，仍在寻找新的、更好的诱导充血的药物。目前，瑞加德松，一种选择性腺苷A2A受体激动剂，似乎具有几乎“理想”的充血刺激特征。
