Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA.
J Neurol Sci. 2013 Dec 15;335(1-2):160-3. doi: 10.1016/j.jns.2013.09.021. Epub 2013 Sep 20.
Persons with multiple sclerosis (MS) commonly have walking and cognitive impairments. While walking with a simultaneous cognitive task, persons with MS experience a greater decline in walking performance than healthy controls. This change in performance is termed dual task cost or dual task interference and has been associated with fall risk in older adults. We examined whether dual task cost during walking was related to fall risk in persons with MS. Thirty-three ambulatory persons with MS performed walking tasks with and without a concurrent cognitive task (dual task condition) as well as underwent a fall risk assessment. Dual task cost was operationalized as the percent change in velocity from normal walking conditions to dual task walking conditions. Fall risk was quantified using the Physiological Profile Assessment. A Spearman correlation analysis revealed a significant positive correlation between dual task cost of walking velocity and fall risk as well as dual task cost of stride length and fall risk. Overall, the findings indicate that dual task cost is associated with fall risk and may be an important target for falls prevention strategies.
多发性硬化症(MS)患者通常存在行走和认知障碍。当进行同时进行认知任务的行走时,MS 患者的行走表现比健康对照组下降更为明显。这种表现的变化被称为双重任务成本或双重任务干扰,并且与老年人的跌倒风险相关。我们研究了多发性硬化症患者行走时的双重任务成本是否与跌倒风险相关。33 名活动能力正常的多发性硬化症患者在进行行走任务时同时进行认知任务(双重任务条件),并进行跌倒风险评估。双重任务成本的计算方法为正常行走条件下与双重任务行走条件下速度的百分比变化。跌倒风险使用生理概况评估进行量化。Spearman 相关性分析显示,行走速度的双重任务成本与跌倒风险以及步长的双重任务成本与跌倒风险之间存在显著正相关。总体而言,这些发现表明双重任务成本与跌倒风险相关,可能是预防跌倒策略的重要目标。