Foissac M, Socolovschi C, Raoult D
Aix Marseille université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France.
Ann Dermatol Venereol. 2013 Oct;140(10):598-609. doi: 10.1016/j.annder.2013.07.014. Epub 2013 Aug 23.
SENLAT syndrome, also known as TIBOLA/DEBONEL, is an emerging disease in France. The major symptoms are necrotic eschar on the scalp associated with painful cervical lymphadenopathy. It occurs mainly in women and children during the cold seasons after a bite by a Dermacentor tick, responsible for transmitting Rickettsia slovaca or Rickettsia raoultii. Cutaneous swabs are safe, easy and reliable tools that should be used routinely by physicians to confirm diagnosis. In this particular disease, they should be preferred to serology, which is less sensitive. Doxycycline is the antibiotic of choice for this syndrome.
SENLAT综合征，也称为TIBOLA/DEBONEL，是法国一种新出现的疾病。主要症状是头皮出现坏死性焦痂并伴有颈部疼痛性淋巴结病。它主要发生在寒冷季节的妇女和儿童身上，是由传播斯洛伐克立克次体或拉乌尔立克次体的篦子硬蜱叮咬后引起的。皮肤拭子是安全、简便且可靠的工具，医生应常规使用以确诊。在这种特定疾病中，应优先选择皮肤拭子而非血清学检查，因为血清学检查敏感性较低。多西环素是该综合征的首选抗生素。
