Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
Dev Cell. 2013 Sep 30;26(6):554-6. doi: 10.1016/j.devcel.2013.09.014.
Recent efforts examining forces during morphogenesis suggest a role for mechanical crosstalk between epithelium and mesenchyme in tissue patterning. Reporting in Science, Shyer et al. (2013) show that differences between the mechanical properties of the developing intestinal epithelium and surrounding smooth muscle fold the epithelium into villi via mucosal buckling.
近期研究形态发生过程中力的作用的成果表明上皮组织和间充质组织之间的力学串扰在组织形态发生中起作用。Shyer 等人在《科学》杂志上报告称（2013 年），发育中的肠上皮组织和周围的平滑肌之间力学特性的差异通过黏膜起皱将上皮组织折叠成绒毛状突起。
