Centre for Suicide Research, University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom; Oxford Health NHS Foundation Trust, Warneford Hospital Oxford, Oxfordshire, United Kingdom.
J Affect Disord. 2013 Dec;151(3):821-30. doi: 10.1016/j.jad.2013.08.020. Epub 2013 Sep 7.
Psychiatric disorders occur in approximately 90% of individuals dying by suicide. The prevalence of psychiatric disorders in people who engage in non-fatal self-harm has received less attention.
Systematic review using electronic databases (Embase, PsychINFO and Medline) for English language publications of studies in which psychiatric disorders have been assessed using research or clinical diagnostic schedules in self-harm patients of all ages presenting to general hospitals, followed by meta-analyses using random effects methods.
A total of 50 studies from 24 countries were identified. Psychiatric (Axis I) disorders were identified in 83.9% (95% CI 74.7-91.3%) of adults and 81.2% (95% CI 60.9-95.5%) of adolescents and young persons. The most frequent disorders were depression, anxiety and alcohol misuse, and additionally attention deficit hyperactivity disorder (ADHD) and conduct disorder in younger patients. Personality (Axis II) disorders were found in 27.5% (95% CI 17.6-38.7%) of adult patients. Psychiatric disorders were somewhat more common in patients in Western (89.6%, 95% CI 83.0-94.7%) than non-Western countries (70.6%, 95% CI 50.1-87.6%).
Heterogeneity between study results was generally high. There were differences between studies in identification of study participants and diagnostic procedures.
Most self-harm patients have psychiatric disorders, as found in people dying by suicide. Depression and anxiety disorders are particularly common, together with ADHD and conduct disorder in adolescents. Psychosocial assessment and aftercare of self-harm patients should include careful screening for such disorders and appropriate therapeutic interventions. Longitudinal studies of the progress of these disorders are required.
精神障碍在约 90%的自杀者中出现。在非致命性自伤者中,精神障碍的患病率受到的关注较少。
系统检索英文文献数据库(Embase、PsychINFO 和 Medline),纳入使用研究或临床诊断性量表评估所有年龄段因自伤就诊于综合医院的自伤患者的精神障碍的研究,然后使用随机效应方法进行荟萃分析。
共纳入来自 24 个国家的 50 项研究。成年人中,有 83.9%(95%CI74.7-91.3%)、青少年和年轻人中,有 81.2%(95%CI60.9-95.5%)存在精神障碍(轴 I)。最常见的疾病是抑郁症、焦虑症和酒精使用障碍,而在年轻患者中还存在注意力缺陷多动障碍(ADHD)和品行障碍。人格障碍(轴 II)在 27.5%(95%CI17.6-38.7%)的成年患者中发现。在西方国家(89.6%,95%CI83.0-94.7%)患者中,精神障碍的发生率高于非西方国家(70.6%,95%CI50.1-87.6%)。
研究结果的异质性普遍较高。研究参与者的确定和诊断程序存在差异。
大多数自伤患者都存在精神障碍,就像自杀者一样。抑郁症和焦虑症尤其常见,青少年中还存在 ADHD 和品行障碍。对自伤患者进行心理社会评估和后续护理应包括对这些障碍的仔细筛查和适当的治疗干预。需要进行这些障碍进展的纵向研究。