Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN, USA; Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA.
Neurosurg Clin N Am. 2013 Oct;24(4):499-507. doi: 10.1016/j.nec.2013.05.006. Epub 2013 Jul 1.
Stereotactic radiosurgery (SRS) has been performed for intracranial meningiomas for more than 30 years. Small to moderate-sized meningiomas are generally considered good candidates for SRS because of their neuro-imaging and radiobiological characteristics. Patient selection is critical for successful meningioma SRS. Factors related to tumor control and radiation-related complications in patients with WHO grade I or presumed meningiomas include history of prior surgery, tumor volume, and tumor location. Patients with small volume, nonoperated skull-base or tentorial meningiomas typically have the best outcomes after SRS.
立体定向放射外科 (SRS) 已用于颅内脑膜瘤超过 30 年。由于其神经影像学和放射生物学特征，小至中等大小的脑膜瘤通常被认为是 SRS 的良好候选者。患者选择对于成功的脑膜瘤 SRS 至关重要。与 WHO 分级 I 或假定脑膜瘤患者的肿瘤控制和放射相关并发症相关的因素包括既往手术史、肿瘤体积和肿瘤位置。对于体积较小、未手术的颅底或天幕脑膜瘤患者，SRS 后的结果通常最好。
