Department of Stereotaxic and Functional Neurosurgery, Gammaknife Unit, La Timone University Hospital, Inserm U751, 264, Rue Saint-Pierre 13385 Marseille Cedex 5, France.
Neurosurg Clin N Am. 2013 Oct;24(4):521-30. doi: 10.1016/j.nec.2013.06.002. Epub 2013 Aug 2.
This article investigates the role of radiosurgery and stereotactic radiotherapy in the management of vestibular schwannomas (VS), reviewing the authors' own prospective cohort and the current literature. For patients with large Stage IV VS (according to the Koos classification), a combined approach with deliberate partial microsurgical removal followed by radiosurgery to the residual tumor is proposed. The authors' cohort is unique with respect to the size of the population and the length of the follow-up, and demonstrates the efficacy and safety of VS radiosurgery, with particular regard to its high rate of hearing preservation.
本文探讨了放射外科和立体定向放射治疗在听神经瘤（VS）治疗中的作用，回顾了作者自己的前瞻性队列研究和当前的文献。对于大型 IV 期 VS（根据 Koos 分类）患者，建议采用联合治疗方法，即先进行有计划的部分显微手术切除，然后对残余肿瘤进行放射外科治疗。作者的队列在人群规模和随访时间方面具有独特性，证明了 VS 放射外科治疗的疗效和安全性，特别是其较高的听力保留率。
