Ghionni A, Miotti T C, Camandona U
Minerva Med. 1985 Jun 8;76(24):1143-8.
In order to estimate the validity of the discriminant function suggested by England e Fraser, we have determined the number of red cells (RBC) mean cell volume (MCV), hemoglobin mean concentration (MCV) and red cells distribution (RDW) in normal subjects, iron-deficient patients and uncomplicated thalassemia minor. The results obtained allow us to point out that RDW in the patients with thalassemia are higher than in normal subjects. In patients with iron-deficiency, instead, RDW medium is increased, but with a remarkable distribution of values. These results point out that anisocytosis is higher in iron-deficiency than in thalassemia.
为了评估英格兰和弗雷泽提出的判别函数的有效性，我们测定了正常受试者、缺铁患者和无并发症轻型地中海贫血患者的红细胞数量（RBC）、平均红细胞体积（MCV）、血红蛋白平均浓度（MCH）和红细胞分布宽度（RDW）。所得结果使我们能够指出，地中海贫血患者的RDW高于正常受试者。相反，缺铁患者的RDW平均值增加，但数值分布显著。这些结果表明，缺铁时的红细胞大小不均比地中海贫血时更高。
