Suppr超能文献

3'-[(1H-吲哚-3-基)羰基]-1'-甲基-2-氧代-4'-(噻吩-2-基)-螺[吲哚啉-3,2'-吡咯烷]-3'-甲腈

3'-[(1H-Indol-3-yl)carbon-yl]-1'-methyl-2-oxo-4'-(thio-phen-2-yl)-spiro-[indoline-3,2'-pyrrolidine]-3'-carbo-nitrile.

作者信息

Inglebert S Antony, Arun Yuvaraj, Sethusankar K, Perumal Paramasivam T

机构信息

Sri Ram Engineering College, Chennai 602 024, India.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2013 Sep 25;69(Pt 10):o1585. doi: 10.1107/S1600536813025890. eCollection 2013.

Abstract

In the title compound, C26H20N4O2S, the central pyrrolidine ring adopts a twist conformation on the C-C bond involving the spiro C atom. Its mean plane makes dihedral angles of 78.83 (14), 65.91 (15) and 44.49 (18)° with the mean planes of the adjacent oxindole ring system, the indole system and the thio-phene ring, respectively. The indole and indoline units are essentially planar, with maximum deviations of 0.019 (3) and 0.090 (3) Å, respectively. In the oxindole fused-ring system, the pyrrole ring adopts an envelope conformation with the spiro C atom as the flap. In the crystal, pairs of N-H⋯O hydrogen bonds link the mol-ecules, forming inversion dimers with an R (2) 2(8) ring motif. The dimers are linked by further N-H⋯O hydrogen bonds, forming a two-dimensional network lying parallel to (100).

摘要

在标题化合物C26H20N4O2S中,中心吡咯烷环在涉及螺碳原子的C-C键上呈扭曲构象。其平均平面与相邻的氧化吲哚环系、吲哚环系和噻吩环的平均平面分别形成78.83 (14)°、65.91 (15)°和44.49 (18)°的二面角。吲哚和二氢吲哚单元基本呈平面状,最大偏差分别为0.019 (3) Å和0.090 (3) Å。在氧化吲哚稠环体系中,吡咯环以螺碳原子为瓣呈信封构象。在晶体中,成对的N-H⋯O氢键连接分子,形成具有R (2) 2(8)环 motif的反演二聚体。二聚体通过进一步的N-H⋯O氢键连接,形成平行于(100)的二维网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8890/3790442/c55898c26c85/e-69-o1585-fig1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验