Royal Free London NHS Foundation Trust, Pond Street, London, NW3 2QG, U.K.
Br J Dermatol. 2013 Oct;169 Suppl 3:11-8. doi: 10.1111/bjd.12527.
Infection with human immunodeficiency virus (HIV) remains a significant problem globally. Early diagnosis and treatment with antiretroviral drugs has considerably improved health outcomes and decreased disease-related morbidity. HIV infection is associated with a wide range of skin disorders enabling dermatologists to diagnose HIV as well as associated opportunistic infections early in the course of disease. Despite concerted efforts by international health organizations to limit disease incidence, the prevalence of HIV infection remains high and is highest in sub-Saharan Africa. The diagnosis of HIV-related skin diseases is challenging as immunosuppression often results in atypical disease presentation. In addition, the clinical presentation will vary in pigmented skin types. The aim of this article is to describe disease variation in pigmented skin types.
人类免疫缺陷病毒(HIV)感染仍然是一个全球性的重大问题。早期诊断和使用抗逆转录病毒药物治疗极大地改善了健康结果,并降低了与疾病相关的发病率。HIV 感染与广泛的皮肤疾病有关,这使皮肤科医生能够在疾病早期诊断 HIV 以及相关的机会性感染。尽管国际卫生组织做出了协调一致的努力来限制疾病的发病率,但 HIV 感染的流行率仍然很高,在撒哈拉以南非洲地区最高。HIV 相关皮肤疾病的诊断具有挑战性,因为免疫抑制通常会导致非典型疾病表现。此外,在色素沉着的皮肤类型中,临床表现也会有所不同。本文的目的是描述色素沉着皮肤类型的疾病变化。