Vigder L, Tzur N, Huber M, Mahagna M, Amir I
Arch Surg. 1985 Jul;120(7):825-8. doi: 10.1001/archsurg.1985.01390310063014.
Of 82 patients who had obstructing cancer of the left colon, 22% had incurable disease and 36.5% had advanced cancer at presentation. All methods of treatment carried a high morbidity and mortality. The mean survival rate with palliative operations was 8.7 months. Twenty-four poor-risk patients treated with staged operations had a 25% operative mortality and a 20.8% five-year survival rate. Forty primary resections, with or without anastomosis, were followed by a 27.5% operative mortality and by more than a twofold five-year survival rate (47.5%) compared with that of staged resection. These results suggest that delay of cure may reduce the late survival rate and justify primary resection as the operation of choice in selected good-risk patients.
在82例患有左半结肠癌梗阻的患者中，22%患有无法治愈的疾病，36.5%在就诊时患有进展期癌症。所有治疗方法都有很高的发病率和死亡率。姑息性手术的平均生存率为8.7个月。接受分期手术治疗的24例高危患者的手术死亡率为25%，五年生存率为20.8%。40例进行了一期切除（无论是否进行吻合）的患者，手术死亡率为27.5%，与分期切除相比，五年生存率提高了两倍多（47.5%）。这些结果表明，延迟治愈可能会降低晚期生存率，并证明一期切除是选定的低风险患者的首选手术方式。
