Desmots F, Chossegros C, Salles F, Gallucci A, Moulin G, Varoquaux A
Department of Radiology, Hôpital d'Instruction des Armées Laveran, BP 60149,13384 Marseille Cedex 13, France.
Aix-Marseille Univ, 13284 Marseille, France; APHM, CHU La Timone, Department of Maxillo-facial Surgery, 13385 Cedex 5, Marseille, France.
J Craniomaxillofac Surg. 2014 Jul;42(5):577-82. doi: 10.1016/j.jcms.2013.07.029. Epub 2013 Sep 5.
To evaluate the predictive value of sonographic fragmentation in the successful treatment of sialolithiasis. The main objective was to streamline the management by treating the patients with three sessions of ultrasonic lithotripsy, and to compare the success rate and complications with data from the literature. A second objective was to analyse the predictive value of data from the post procedure and follow-up sonography related to therapeutic success with regard to size, site and location of stones.
Prospective follow-up of 25 patients (mean age of 43 ± 17.2 years old 11-68; 13 women, 10 men) over a period of 31 months (October 2009-April 2012) with one or more salivary calculi (19 parotid, submandibular 6) treated with extracorporeal lithotripsy (electromagnetic MINILITH SL 1, Storz Medical, Switzerland). No anaesthesia or analgesia was used. Each session of lithotripsy lasted on average 30 min. Minor complications were collected on an anonymised sheet.
Complete success (absence of clinical symptoms 3 months after the end of treatment (or the last session) and residual stones <2 mm) was observed in 36% of patients, partial success (persistence of symptoms least 3 months (lower intensity and lower frequency) or size of residual stones>2 mm) in 48% and failure (persistence of same or increased symptoms at 3 months or no change in size of the calculi) in 17% of patients. Sonographic fragmentation of the stone (p = 0.004), total energy delivered (p = 0.008) and the total number of shock waves (n = 0.045) are predictive factors of complete success. Size, salivary topography, ductal topography, mobilization of the stones, occurrence of minor side effects and total duration of treatment had no predictive value of complete success (p > 0.05). There was no significant difference between the first 5 and the last 20 patients (p = 0.367). In agreement with the literature data, the efficacy of treatment was greater for parotid than submandibular calculi.
Extracorporeal lithotripsy is an alternative to conventional surgery with no major complications. Sonographic fragmentation of calculi, total energy and total number of shock waves are predictive factors of successful treatment.
评估超声碎石在涎石病成功治疗中的预测价值。主要目的是通过对患者进行三次超声碎石治疗来简化治疗管理,并将成功率和并发症与文献数据进行比较。第二个目的是分析治疗后及随访超声检查数据在结石大小、部位和位置方面对治疗成功的预测价值。
对25例患者(平均年龄43±17.2岁,11 - 68岁;13名女性,10名男性)进行了为期31个月(2009年10月 - 2012年4月)的前瞻性随访,这些患者患有一个或多个涎腺结石(19例腮腺结石,6例下颌下腺结石),采用体外冲击波碎石术(瑞士Storz Medical公司的电磁MINILITH SL 1)进行治疗。未使用麻醉或镇痛措施。每次碎石治疗平均持续30分钟。轻微并发症通过匿名表格进行收集。
36%的患者获得完全成功(治疗结束后3个月(或最后一次治疗后)无临床症状且残余结石<2mm),48%的患者部分成功(症状持续至少3个月(强度和频率降低)或残余结石大小>2mm),17%的患者治疗失败(3个月时症状持续或加重或结石大小无变化)。结石的超声碎石情况(p = 0.004)、总能量(p = 0.008)和冲击波总数(n = 0.045)是完全成功的预测因素。结石大小、涎腺位置、导管位置、结石移动情况、轻微副作用的发生及治疗总时长对完全成功无预测价值(p>0.05)。前5例患者与后20例患者之间无显著差异(p = 0.367)。与文献数据一致,腮腺结石的治疗效果优于下颌下腺结石。
体外冲击波碎石术是传统手术的一种替代方法,无重大并发症。结石的超声碎石情况、总能量和冲击波总数是治疗成功的预测因素。