Xuejian Wang, Xiaobiao Zhang, Fan Hu, Yong Yu, Ye Gu, Tao Xie
Fudan University, Zhongshan Hospital, Department of Neurosurgery, Shanghai, China.
Turk Neurosurg. 2013;23(4):543-5. doi: 10.5137/1019-5149.JTN.5514-11.2.
Brain parenchyma schwannoma is a rare intracranial tumor, and especially rare in cerebellar hemisphere. In this report, a case of cerebellar schwannoma in a 52-year-old woman, was studied by computed tomography (CT), magnetic resonance image (MRI) and PET-CT. This tumor was totally removed by surgery. The histological diagnosis of schwannoma was confirmed by histological, HE and immunohistological staining examination (positivity for the S-100 protein and vimentin, and partly positivity for P53 (70 %+), and negative for GFAP). The patient has been followed-up for more than one year, and she lives in good condition and brain MRI shows no recurrence. Surgery is the most effective treatment for cerebellar schwannoma.
脑实质神经鞘瘤是一种罕见的颅内肿瘤,在小脑半球尤为罕见。在本报告中,对一名52岁女性的小脑神经鞘瘤病例进行了计算机断层扫描(CT)、磁共振成像(MRI)和正电子发射断层显像-CT(PET-CT)研究。该肿瘤通过手术完全切除。通过组织学、苏木精-伊红(HE)和免疫组织化学染色检查确诊为神经鞘瘤(S-100蛋白和波形蛋白呈阳性,P53部分阳性(70%+),胶质纤维酸性蛋白(GFAP)呈阴性)。该患者已随访一年多,她生活状况良好,脑部MRI显示无复发。手术是治疗小脑神经鞘瘤最有效的方法。