Alhantoobi Mohamed, Alkhoori Nadeen, Khayat Hassan, Zhang Euan, Algird Almunder, Provias John
Department of Neurosurgery, Hamilton General Hospital, McMaster University Medical Centre, 237 Barton St E., Hamilton, Ontario, Canada L8L 2X2.
Department of Neurosurgery, Zayed Military Hospital, Abu Dhabi, UAE.
Case Rep Pathol. 2024 Oct 16;2024:8678186. doi: 10.1155/2024/8678186. eCollection 2024.
Intracerebellar schwannoma is an extremely rare disease entity with only 21 case reports described in the literature. A 68-year-old male presented with chronic headaches, dizziness, gait imbalance, and incoordination. Previous MRI had revealed a cystic lesion in the right cerebellum; however, patient was lost to follow-up. Updated MRI revealed dramatic enlargement of the lesion in addition to worsening clinical status. The patient underwent successful surgical resection. Intracerebellar schwannoma can be challenging to diagnose preoperatively due to its rare occurrence; however, it should be included in the differential diagnosis of cystic lesions in the cerebellum, and most cases can be successfully treated with complete surgical resection. Pathological examination revealed a spindle cell neoplasm with other typical histopathological features of schwannoma.
小脑内神经鞘瘤是一种极其罕见的疾病实体,文献中仅描述了21例病例报告。一名68岁男性出现慢性头痛、头晕、步态不稳和共济失调。先前的MRI显示右侧小脑有一个囊性病变;然而,患者失访。更新后的MRI显示病变显著增大,临床症状也恶化。该患者接受了成功的手术切除。由于小脑内神经鞘瘤罕见,术前诊断可能具有挑战性;然而,它应列入小脑囊性病变的鉴别诊断中,大多数病例通过完全手术切除可成功治疗。病理检查显示为梭形细胞瘤,具有神经鞘瘤的其他典型组织病理学特征。