Suppr超能文献

计算机断层扫描在部分性癫痫患儿中的临床诊断及治疗意义

Clinico - diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures.

作者信息

Patel Nehal H, Jain Ashish R, Iyer Vivek K, Shah Anand G, Jain Dipti A, Shah Anjanaben A

机构信息

Department of Pediatrics, GMERS Medical College Sola, Ahmedabad, Gujarat, India.

出版信息

Ann Indian Acad Neurol. 2013 Jul;16(3):352-6. doi: 10.4103/0972-2327.116928.

Abstract

BACKGROUND

Therapeutic relevance of computed tomography (CT) in children with partial seizures is reported to be remarkably low (1-2%). However, in the developing countries where infections involving the nervous system are common, routine CT scan of brain may help in finding treatable causes of seizures.

OBJECTIVE

Aim of this study was to evaluate the significance of CT scan of brain in the management of children with partial seizures.

MATERIALS AND METHODS

Children with partial epilepsy, whose predominant seizure type was focal motor seizures, were included in the study. CT scan of brain was done in all children aged between 1 month and 12 years with partial seizures of unknown etiology prospectively. The clinical findings of these children were noted along with the CT findings.

RESULTS

Between August 2001 and July 2002, of the 200 children with seizure disorder 50 children who satisfied the inclusion criteria were included in the study. CT scan of brain was normal in 16 children (32%) and was abnormal in 34 children (68%). Twenty children (~60% of abnormal scan) had potentially correctable lesions: Tuberculoma (n = 13), neurocysticercosis (n = 3), and brain abscess (n = 4). Five children had changes representing static pathology that did not influence patient management. The clinical features correlated with CT findings in 78% children.

CONCLUSION

Children with partial motor seizures have high probability of having abnormal findings on CT scan of brain, especially, neuro-infections which are potentially treatable. Therefore, CT scan brain should be carried out in all children with partial motor seizures especially, in developing countries.

摘要

背景

据报道,计算机断层扫描(CT)在部分性癫痫患儿中的治疗相关性非常低(1%-2%)。然而,在神经系统感染常见的发展中国家,常规脑部CT扫描可能有助于发现可治疗的癫痫病因。

目的

本研究旨在评估脑部CT扫描在部分性癫痫患儿管理中的意义。

材料与方法

纳入以局灶性运动性癫痫为主要发作类型的部分性癫痫患儿。对所有年龄在1个月至12岁、病因不明的部分性癫痫患儿进行前瞻性脑部CT扫描。记录这些患儿的临床发现以及CT结果。

结果

在2001年8月至2002年7月期间,200例癫痫患儿中有50例符合纳入标准并被纳入研究。16例患儿(占32%)的脑部CT扫描结果正常,34例患儿(占68%)的结果异常。20例患儿(约占异常扫描患儿的60%)有潜在可纠正的病变:结核瘤(13例)、脑囊尾蚴病(3例)和脑脓肿(4例)。5例患儿有代表静止性病变的改变,不影响患者的治疗管理。78%的患儿临床特征与CT结果相关。

结论

部分性运动性癫痫患儿脑部CT扫描出现异常结果的可能性很高,尤其是潜在可治疗的神经感染。因此,所有部分性运动性癫痫患儿都应进行脑部CT扫描,特别是在发展中国家。

相似文献

2
CT in simple partial seizures in children: a clinical and computed tomography study.
Acta Neurol Scand. 1997 Apr;95(4):197-200. doi: 10.1111/j.1600-0404.1997.tb00098.x.
6
Computerized tomography of children with seizure disorders.
Niger J Clin Pract. 2009 Mar;12(1):25-8.
7
Computerized Axial Tomography Findings in Children with Afebrile Seizures: A Hospital Based Study at Eastern Nepal.
J Nepal Health Res Counc. 2017 Jan;15(1):61-66. doi: 10.3126/jnhrc.v15i1.18015.
8
Computed tomography findings in partial seizures.
Arch Dis Child. 1992 Jun;67(6):693-6. doi: 10.1136/adc.67.6.693.

引用本文的文献

1
Neuroimaging of first-ever seizure: Contribution of MRI if CT is normal.
Neurol Clin Pract. 2014 Feb;4(1):2. doi: 10.1212/01.CPJ.0000442688.05566.eb.

本文引用的文献

1
Diagnosis and treatment of neurocysticercosis.
Interdiscip Perspect Infect Dis. 2009;2009:180742. doi: 10.1155/2009/180742. Epub 2009 Aug 27.
2
Neuroimaging of epilepsy: therapeutic implications.
NeuroRx. 2005 Apr;2(2):384-93. doi: 10.1602/neurorx.2.2.384.
5
CT in simple partial seizures in children: a clinical and computed tomography study.
Acta Neurol Scand. 1997 Apr;95(4):197-200. doi: 10.1111/j.1600-0404.1997.tb00098.x.
6
Focal electroencephalographic abnormalities and computerised tomography findings in children with seizures.
J Neurol Neurosurg Psychiatry. 1993 Apr;56(4):369-71. doi: 10.1136/jnnp.56.4.369.
7
Intracranial tuberculomas: a CT study.
Br J Radiol. 1980 Oct;53(634):935-45. doi: 10.1259/0007-1285-53-634-935.
8
The role of computed cranial tomography (CT) in epilepsy.
Can J Neurol Sci. 1983 Feb;10(1):16-21. doi: 10.1017/s0317167100044504.
9
Computerized tomography in epilepsy: a five year experience.
Electroencephalogr Clin Neurophysiol Suppl. 1982(35):223-32.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验