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儿童单纯部分性发作的CT:一项临床与计算机断层扫描研究

CT in simple partial seizures in children: a clinical and computed tomography study.

作者信息

Nair K P, Jayakumar P N, Taly A B, Arunodya G R, Swamy H S, Shanmugam V

机构信息

Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India.

出版信息

Acta Neurol Scand. 1997 Apr;95(4):197-200. doi: 10.1111/j.1600-0404.1997.tb00098.x.

DOI:10.1111/j.1600-0404.1997.tb00098.x
PMID:9150808
Abstract

INTRODUCTION

Therapeutic relevance of computed tomography (CT) in children with simple partial seizures (SPS) is reported to be remarkably low (1-2%). There are not studies, however, from the developing countries where neuroinfections are among important causes of seizures. The present study from India is aimed at evaluating the significance of CT in the management of SPS in children and to determine the difference in clinical features of children with and without focal brain lesions in CT.

PATIENTS AND METHODS

CT scans of all patients aged 15 years of younger with SPS, seen over a period of 15 months, were reviewed. The clinical features of the patients with focal lesions in the CT were compared with those of children without focal abnormalities.

RESULTS

Focal structural lesions were present in 117 (59.09%) of 198 children. These included: solitary contrast enhancing CT lesion-16.16%, focal calcification-12.12%, cysticerosis-10.10%, focal atrophy-9.59%, tuberculoma-6.56% and infarction-6.06%. Neuroinfections or their sequelae were responsible for seizures in 89 children (44.94%). There were no statistically significant differences in clinical features of patients with and without focal lesions in CT.

CONCLUSIONS

CT study in children with SPS in developing countries has significant therapeutic relevance. It is not possible to clinically differentiate children with focal lesions from those without focal lesions in CT.

摘要

引言

据报道,计算机断层扫描(CT)在单纯部分性发作(SPS)儿童中的治疗相关性非常低(1%-2%)。然而,在神经感染是癫痫重要病因之一的发展中国家,尚无相关研究。印度的这项研究旨在评估CT在儿童SPS管理中的意义,并确定CT检查有和无局灶性脑病变的儿童临床特征的差异。

患者与方法

回顾了15个月内就诊的所有15岁及以下SPS患儿的CT扫描结果。将CT有局灶性病变患儿的临床特征与无局灶性异常的患儿进行比较。

结果

198例患儿中117例(59.09%)存在局灶性结构病变。这些病变包括:孤立性强化CT病变-16.16%、局灶性钙化-12.12%、囊尾蚴病-10.10%、局灶性萎缩-9.59%、结核瘤-6.56%和梗死-6.06%。89例患儿(44.94%)的癫痫发作由神经感染或其后遗症引起。CT有和无局灶性病变的患者临床特征无统计学显著差异。

结论

发展中国家SPS患儿的CT研究具有重要的治疗意义。临床上无法区分CT有局灶性病变和无局灶性病变的儿童。

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