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The generative grammar of the immune system.

作者信息

Jerne N K

出版信息

EMBO J. 1985 Apr;4(4):847-52. doi: 10.1002/j.1460-2075.1985.tb03709.x.

DOI:10.1002/j.1460-2075.1985.tb03709.x
PMID:2410261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC554270/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b8/554270/6cdf6fb54ecb/emboj00269-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b8/554270/dd7af0764b67/emboj00269-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b8/554270/6cdf6fb54ecb/emboj00269-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b8/554270/dd7af0764b67/emboj00269-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9b8/554270/6cdf6fb54ecb/emboj00269-0010-a.jpg

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1
The generative grammar of the immune system.免疫系统的生成语法。
EMBO J. 1985 Apr;4(4):847-52. doi: 10.1002/j.1460-2075.1985.tb03709.x.
2
The generative grammar of the immune system. Nobel lecture, 8 December 1984.
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Is the immune system a functional idiotypic network?免疫系统是一个功能性独特型网络吗？
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5
The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1984. The generative grammar of the immune system.
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[Anti-idiotypes. The prospects for their use in microbiology].
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Immune modulation and possible pathological implications mediated by naturally produced immunoglobulin G idiotypes: from historical to recent experimental and clinical studies focused on atopic dermatitis.天然产生的免疫球蛋白G独特型介导的免疫调节及可能的病理意义：从历史研究到近期聚焦特应性皮炎的实验与临床研究
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本文引用的文献

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The hydrolysis of rabbit y-globulin and antibodies with crystalline papain.用结晶木瓜蛋白酶对兔γ球蛋白和抗体进行水解。
Biochem J. 1959 Sep;73(1):119-26. doi: 10.1042/bj0730119.
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Cellular antibodies in kidney homotransplantation.肾脏同种移植中的细胞抗体。
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The self-nonself discrimination and the nature and acquisition of the antibody repertoire.自身与非自身的识别以及抗体库的性质与获得。
Conversion and Obsessive-Phobic Symptoms Predict IL-33 and IL-28A Levels in Individuals Diagnosed with COVID-19.
转换症状和强迫-恐惧症状可预测新冠病毒病确诊患者的白细胞介素-33和白细胞介素-28A水平
Brain Sci. 2023 Aug 31;13(9):1271. doi: 10.3390/brainsci13091271.
4
The Molecular Mechanisms That Underlie the Immune Biology of Anti-drug Antibody Formation Following Treatment With Monoclonal Antibodies.单克隆抗体治疗后形成抗药物抗体的免疫生物学的分子机制。
Front Immunol. 2020 Aug 18;11:1951. doi: 10.3389/fimmu.2020.01951. eCollection 2020.
5
Immunogenicity of Innovative and Biosimilar Monoclonal Antibodies.创新型和生物类似单克隆抗体的免疫原性
Antibodies (Basel). 2019 Mar 5;8(1):21. doi: 10.3390/antib8010021.
6
Development of an Anti-Idiotypic VHH Antibody and Toxin-Free Enzyme Immunoassay for Ochratoxin A in Cereals.开发一种针对谷物中赭曲霉毒素 A 的抗独特型 VH 抗体和无毒素酶免疫分析方法。
Toxins (Basel). 2019 May 20;11(5):280. doi: 10.3390/toxins11050280.
7
Immune Response Regulation by Antigen Receptors' Clone-Specific Nonself Parts.抗原受体克隆特异性非自身部分对免疫反应的调节
Front Immunol. 2018 Jun 25;9:1471. doi: 10.3389/fimmu.2018.01471. eCollection 2018.
8
Mechanism of the antigen-independent cytokinergic SPE-7 IgE activation of human mast cells in vitro.体外人肥大细胞抗原非依赖性细胞因子介导的SPE-7 IgE激活机制。
Sci Rep. 2015 Apr 20;5:9538. doi: 10.1038/srep09538.
9
Self-tolerance in a minimal model of the idiotypic network.独特型网络最小模型中的自身耐受性
Front Immunol. 2014 Mar 10;5:86. doi: 10.3389/fimmu.2014.00086. eCollection 2014.
10
Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission.一项二价神经节苷脂疫苗联合β-葡聚糖用于高危神经母细胞瘤二线或后续缓解期的I期试验。
Clin Cancer Res. 2014 Mar 1;20(5):1375-82. doi: 10.1158/1078-0432.CCR-13-1012. Epub 2014 Feb 11.
Ann Immunol (Paris). 1980 Nov-Dec;131D(3):235-53.
4
Recurrent idiotopes and internal images.复发性独特型位和内影像
EMBO J. 1982;1(2):243-7. doi: 10.1002/j.1460-2075.1982.tb01154.x.
5
Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain.免疫球蛋白重链可变区基因的体细胞突变。
Science. 1982 Apr 16;216(4543):309-11. doi: 10.1126/science.6801765.
6
Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody.通过单克隆抗独特型抗体和携带独特型抗体控制独特型表位表达。
Eur J Immunol. 1981 May;11(5):418-23. doi: 10.1002/eji.1830110513.
7
Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.重链可变区对NPb抗体家族的贡献：γ2a可变区中明显的体细胞突变。
Cell. 1981 Jun;24(3):625-37. doi: 10.1016/0092-8674(81)90089-1.
8
Somatic diversification of immunoglobulins.免疫球蛋白的体细胞多样化
Proc Natl Acad Sci U S A. 1984 Apr;81(7):2162-6. doi: 10.1073/pnas.81.7.2162.
9
Genetics, expression, and function of idiotypes.独特型的遗传学、表达及功能
Annu Rev Immunol. 1983;1:569-607. doi: 10.1146/annurev.iy.01.040183.003033.
10
From an antigen-centered, clonal perspective of immune responses to an organism-centered, network perspective of autonomous activity in a self-referential immune system.从以抗原为中心的免疫反应克隆视角，到以生物体为中心的自我参照免疫系统自主活动网络视角。
Immunol Rev. 1984 Jun;79:151-68. doi: 10.1111/j.1600-065x.1984.tb00492.x.