兔科 Oryctolagus、Sylvilagus 和 Lepus 属中 CCL3、CCL4 和 CCL5 的遗传特征。
Genetic characterization of CCL3, CCL4 and CCL5 in leporid genera Oryctolagus, Sylvilagus and Lepus.
机构信息
CIBIO - Centro de Investigação em Biodiversidade e Recursos Genéticos/InBio Laboratório Associado, Universidade do Porto, Vairão, Portugal; Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Porto, Portugal; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
出版信息
Int J Immunogenet. 2014 Apr;41(2):154-8. doi: 10.1111/iji.12095. Epub 2013 Sep 19.
The genetic diversity of C-C motif chemokine receptor 5 (CCR5) ligands CCL3, CCL4 and CCL5 in the leporid genera Oryctolagus, Sylvilagus and Lepus was studied. Our results demonstrate that the three CCR5 chemokine ligands are under strong purifying selection as a result of possible functional binding constraints.
研究了兔形目兔属、林兔属和兔属中 C-C 基序趋化因子受体 5（CCR5）配体 CCL3、CCL4 和 CCL5 的遗传多样性。研究结果表明，这三种 CCR5 趋化因子配体受到强烈的纯化选择，这可能是由于功能结合的约束。
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