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活体肝移植治疗尾状叶肝细胞癌时肝后下腔静脉去顶术。

Retrohepatic vena cava deroofing in living donor liver transplantation for caudate hepatocellular carcinoma.

机构信息

Department of Surgery; State Key Laboratory for Liver Research, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China.

出版信息

Hepatobiliary Pancreat Dis Int. 2013 Oct;12(5):552-5. doi: 10.1016/s1499-3872(13)60087-9.

Abstract

The removal of tumor together with the native liver in living donor liver transplantation for hepatocellular carcinoma is challenged by a very close resection margin if the tumor abuts the inferior vena cava. This is in contrast to typical deceased donor liver transplantation where the entire retrohepatic inferior vena cava is included in total hepatectomy. Here we report a case of deroofing the retrohepatic vena cava in living donor liver transplantation for caudate hepatocellular carcinoma. In order to ensure clear resection margins, the anterior portion of the inferior vena cava was included. The right liver graft was inset into a Dacron vascular graft on the back table and the composite graft was then implanted to the recipient inferior vena cava. Using this technique, we observed the no-touch technique in tumor removal, hence minimizing the chance of positive resection margin as well as the chance of shedding of tumor cells during manipulation in operation.

摘要

在活体肝移植中,如果肿瘤紧邻下腔静脉,那么连同供体肝一并切除肿瘤会面临非常接近的切缘。这与典型的尸体供肝移植不同,后者的整个肝后下腔静脉都包含在全肝切除术中。在这里,我们报告了一例活体肝移植治疗尾状叶肝细胞癌时对肝后下腔静脉去顶的病例。为了确保清晰的切缘,我们包括了下腔静脉的前部。右肝移植物被插入背侧的 Dacron 血管移植物中,然后将复合移植物植入受者的下腔静脉。使用这种技术,我们观察到了在肿瘤切除过程中采用无接触技术,从而最大限度地减少了阳性切缘的机会,以及在手术操作过程中肿瘤细胞脱落的机会。

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