Lewis Gwyn N, Signal Nada, Taylor Denise
Health and Rehabilitation Research Institute, AUT University, Auckland, New Zealand.
Health and Rehabilitation Research Institute, AUT University, Auckland, New Zealand.
Clin Neurophysiol. 2014 Apr;125(4):748-754. doi: 10.1016/j.clinph.2013.07.029. Epub 2013 Oct 5.
To determine the intra- and inter-session reliability of motor evoked potential (MEP) size parameters in the lower limb of patients with stroke, focussing on the number of MEPs collected and the method of measuring MEP size.
Transcranial magnetic stimulation was used to elicit MEPs in the soleus muscle of patients with stroke (n=13) and age-matched healthy participants (n=13) during low level muscle activation. Two sets of 10 responses were collected in the first session and a further 10 responses collected in a second session held 7 days later. Four MEP size measurements were made using 4, 6, 8, or all 10 of the MEPs collected. Intra- and inter-session reliability was examined using intraclass correlation coefficients (ICC) and typical percentage error.
Intrasession ICC statistics using 6 or more MEPs were >0.85 in the stroke group but intersession values were all <0.5. Reliability was best when measuring parameters from individual MEPs rather than averaged responses.
Reliability of intrasession MEP size is excellent in the lower limb of patients with stroke using as few as 6 MEPs but intersession reliability is poor.
Comparing MEP size measures across two or more sessions is questionable in the lower limb of patients with stroke.
确定中风患者下肢运动诱发电位（MEP）大小参数在不同时段内及不同时段间的可靠性，重点关注收集的MEP数量和测量MEP大小的方法。
在低水平肌肉激活期间，采用经颅磁刺激诱发中风患者（n = 13）和年龄匹配的健康参与者（n = 13）比目鱼肌的MEP。在第一时段收集两组10个反应，并在7天后的第二时段再收集10个反应。使用收集到的4、6、8个或全部10个MEP进行4次MEP大小测量。使用组内相关系数（ICC）和典型百分比误差检查不同时段内及不同时段间的可靠性。
中风组使用6个或更多MEP的时段内ICC统计值>0.85，但不同时段间的值均<0.5。测量单个MEP的参数而非平均反应时，可靠性最佳。
中风患者下肢使用低至6个MEP时，时段内MEP大小的可靠性极佳，但不同时段间的可靠性较差。
在中风患者下肢比较两个或更多时段的MEP大小测量结果存在疑问。
