Department of Neurology, University Hospitals Case Medical Center, 3619 Park East Drive, suite 211, Beachwood, OH, 44122, USA.
Curr Cardiol Rep. 2013 Dec;15(12):427. doi: 10.1007/s11886-013-0427-6.
Small vessel disease (SVD) in the brain manifests in the periventricular and deep white matter and radiographically is described as "leukoaraiosis". It is increasingly recognized as a cause of morbidity from middle age onward and this clinical relevance has paralleled advances in the field of neuroradiology. Overall, SVD is a heterogenous group of vascular disorders that may be asymptomatic, or a harbinger of many conditions that jeopardize brain health. Management and prevention focuses on blood pressure control, lifestyle modification, and symptomatic treatment.
脑小血管病（SVD）表现为脑室周围和深部白质，影像学上描述为“脑白质疏松症”。它越来越被认为是中年以后发病和致残的原因，这种临床相关性与神经放射学领域的进展是平行的。总的来说，SVD 是一组异质性的血管疾病，可能无症状，也可能是许多危及大脑健康的疾病的先兆。治疗和预防的重点是控制血压、改变生活方式和对症治疗。
