用荧光分光光度法测定药物制剂中的水杨酸和苯甲酸。
The determination of salicylic acid and benzoic acid in pharmaceutical formulations by spectrofluorimetry.
作者信息
Adams S, Miller J H
出版信息
J Pharm Pharmacol. 1978 Feb;30(2):81-3. doi: 10.1111/j.2042-7158.1978.tb13166.x.
Abstract
Methods of extraction from pharmaceutical formulations and subsequent determination of benzoic acid and salicylic acid by spectrofluorimetry are described. The recovery of benzoic acid, in the presence of salicylic acid, was 99.3%, with a coefficient of variation of 1.04%, while the recovery of salicylic acid, in the presence of benzoic acid, was 97.7%, with a coefficient of variation of 0-68%.
摘要
描述了从药物制剂中提取苯甲酸和水杨酸并随后用荧光分光光度法进行测定的方法。在水杨酸存在下，苯甲酸的回收率为99.3%，变异系数为1.04%；而在苯甲酸存在下，水杨酸的回收率为97.7%，变异系数为0.68%。
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