[Expression in Chinese hamster transformant TK+-cells of the bacterial gene for beta-lactamase].
作者信息
Tomilin N V, Glebov O K, Mikhaĭlov V M, Sasina L K, Abramian D S
出版信息
Tsitologiia. 1985 Jun;27(6):688-92.
PMID:2411034
Abstract
Using monospecific immune antiserum the expression of beta-lactamase bacterial gene (from the plasmid pBR322) in transformed TK+ Chinese hamster cells was studied. It is shown that in some TK+-clones the beta-lactamase gene is expressed and this expression is stimulated by an inhibitor of DNA methylation-5-azacytidine. Two physically linked genes (the Herpes simplex thymidine kinase gene, and the beta-lactamase gene) introduced into the Chinese hamster cells on the same plasmid are found to be expressed independently.
摘要
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[Expression in Chinese hamster transformant TK+-cells of the bacterial gene for beta-lactamase].
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