Song Kang-Il, Shon Ahnsei, Chu Jun-Uk, Choi Kuiwon, Hwang Dosik, Youn Inchan
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:3610-3. doi: 10.1109/EMBC.2013.6610324.
An implantable wireless system was developed for recording muscle afferent activity and stimulating peripheral nerves with cuff electrodes. The proposed system was fabricated into the nerve cuff electrode, neural amplifier, neural stimulator, and wireless communication system with battery power. The nerve cuff electrode and neural amplifier were designed to improve the signal-to-interference ratio and signal-to-noise ratio. The wireless communication system was designed based on the medical implant communication service regulations to be suitable for implantation. The main function of this system was to extract muscle afferent activity from peripheral nerve during functional electrical stimulation. The cuff electrodes were chronically implanted on the sciatic nerve for recording and on the tibial and peroneal nerves for stimulation. When the extension and flexion movements of ankle joint were elicited from alternative electrical stimuli, the corresponding neural signals and ankle angles were recorded simultaneously. The muscle afferent activity was then extracted from the recorded neural signal through a simple blanking process. The experimental results showed that the ankle movements could be detected from the extracted muscle afferent activity.
开发了一种可植入无线系统，用于记录肌肉传入活动并通过袖带电极刺激周围神经。所提出的系统被制作成神经袖带电极、神经放大器、神经刺激器以及带有电池供电的无线通信系统。神经袖带电极和神经放大器旨在提高信号干扰比和信噪比。无线通信系统是根据医疗植入通信服务规定设计的，以适合植入。该系统的主要功能是在功能性电刺激期间从周围神经中提取肌肉传入活动。袖带电极被长期植入坐骨神经用于记录，以及植入胫神经和腓总神经用于刺激。当通过交替电刺激引发踝关节的屈伸运动时，同时记录相应的神经信号和踝关节角度。然后通过简单的消隐过程从记录的神经信号中提取肌肉传入活动。实验结果表明，可以从提取的肌肉传入活动中检测到踝关节运动。
