Ju Kuen-Cheng, Fu Shen-Li
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:3729-32. doi: 10.1109/EMBC.2013.6610354.
Phased array transducer has the ability to generate multiple-focus pattern by adjusting the driving signal of individual element of the array. For the treatment of large target volume, several multiple-focus pattern could be used by using temporal switching technique among these power patterns. Typically, to obtain a uniform thermal dose, properly adjust the power level within the target volume is important. In this study, we proposed a temperature feedback based heating strategy without the need of power level adjustment. Several parameters, such as the setting temperature, sonication time, power level and blood perfusion, may affect the final thermal dose. Simulation results show that setting temperature is the key parameter to determine the final thermal dose while the effects of blood perfusion could be neglected and the sonication time should be as short as possible. Small power level is not suggested because the resulting thermal dose would extended owing to the thermal conduction.
相控阵换能器能够通过调整阵列中各个元件的驱动信号来生成多个聚焦模式。对于大目标体积的治疗，可以通过在这些功率模式之间使用时间切换技术来使用几种多个聚焦模式。通常，为了获得均匀的热剂量，在目标体积内适当调整功率水平很重要。在本研究中，我们提出了一种基于温度反馈的加热策略，无需调整功率水平。几个参数，如设定温度、超声处理时间、功率水平和血液灌注，可能会影响最终的热剂量。模拟结果表明，设定温度是决定最终热剂量的关键参数，而血液灌注的影响可以忽略不计，超声处理时间应尽可能短。不建议使用小功率水平，因为由于热传导，产生的热剂量会扩大。
