Wang Hui, Stoeck Christian T, Kozerke Sebastian, Amini Amir A
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:4386-9. doi: 10.1109/EMBC.2013.6610518.
In this paper, we propose a novel 3D sine wave modeling (3D SinMod) approach to automatic analysis of 3D cardiac deformations. An accelerated 3D complementary spatial modulation of magnetization (CSPAMM) tagging technique was used to modulate the myocardial tissue and to acquire 3D MR data sets of the whole-heart including three orthog- onal tags within three breath-holds. Each tag set is able to assess the motion along a direction perpendicular to the tag lines. With the application of CSPAMM, the effect of tag fading encountered in SPAMM tagging due to T1 relaxation is mitigated and tag deformations can be visualized for the entire cardiac cycle, including diastolic phases. In the proposed approach, the environment around each voxel in the 3D volume is modeled as a moving sine wavefront with local frequency and amplitude. The biggest advantage of the proposed technique is that the entire framework, from data acquisition to data analysis is in the 3D domain, which permits quantification of both the in-plane and through-plane motion components. The accuracy and the effectiveness of the proposed method has been validated using both simulated and in vivo tag data.
在本文中，我们提出了一种新颖的三维正弦波建模（3D SinMod）方法，用于三维心脏变形的自动分析。采用了一种加速的三维磁化互补空间调制（CSPAMM）标记技术来调制心肌组织，并在三次屏气内获取包含三个正交标记的全心三维磁共振数据集。每个标记集能够评估沿垂直于标记线方向的运动。通过应用CSPAMM，减轻了由于T1弛豫在SPAMM标记中遇到的标记衰减效应，并且可以在包括舒张期在内的整个心动周期中可视化标记变形。在所提出的方法中，三维体积中每个体素周围的环境被建模为具有局部频率和幅度的移动正弦波前。所提出技术的最大优点是，从数据采集到数据分析的整个框架都在三维域中，这允许对平面内和平面间的运动分量进行量化。所提出方法的准确性和有效性已通过模拟和体内标记数据得到验证。
