Kobayashi Tetsuo, Akamatsu Koichiro, Natsukawa Hiroaki
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:5414-7. doi: 10.1109/EMBC.2013.6610773.
Binocular rivalry occurs over time when each eye is simultaneously presented with different visual stimuli. We have addressed which brain regions are and the mechanisms involved in binocular rivalry using EEG and fMRI measurements of cortical activities during observations of competitive (rivalry) and cooperative (fusion) drifting vertical gratings. By applying an EEG-fMRI integrative method, we analyzed the time courses of multiple cortical sources of event-related potentials obtained under rivalry or fusion conditions. We detected significant cortical activities at bilateral MT+/V5 and the right prefrontal eye field in the rivalry condition; however, this may not reflect intrinsic alternation in binocular rivalry. Our findings suggest that novel integrative methods are necessary to investigate the distributed cortical network associated with binocular rivalry, through analysis of multiple cortical sources of event-related desynchronization and/or synchronization in certain frequency bands.
当每只眼睛同时呈现不同的视觉刺激时，会随着时间出现双眼竞争现象。我们利用脑电图（EEG）和功能磁共振成像（fMRI）对观察竞争性（竞争）和合作性（融合）垂直漂移光栅时的皮层活动进行测量，探讨了参与双眼竞争的脑区及其机制。通过应用EEG-fMRI整合方法，我们分析了在竞争或融合条件下获得的事件相关电位的多个皮层源的时间进程。我们在竞争条件下检测到双侧MT+/V5和右侧前额叶眼区有显著的皮层活动；然而，这可能并不反映双眼竞争中的内在交替。我们的研究结果表明，有必要采用新的整合方法，通过分析特定频段内事件相关去同步化和/或同步化的多个皮层源，来研究与双眼竞争相关的分布式皮层网络。
