Freij L, Hebelka M, Seeberg S
Scand J Infect Dis. 1975;7(2):153-5. doi: 10.3109/inf.1975.7.issue-2.13.
A 63-year-old woman developed pneumococcal meningitis during cephalothin treatment for pneumococcal septicaemia. The poor penetration of this antibiotic over the blood-brain barrier makes it unsuitable for the therapy of meningitis. If cephalothin is used in other serious infections, the patient should be closely observed for the development of meningitis.
一名63岁女性在接受头孢噻吩治疗肺炎球菌败血症期间发生了肺炎球菌脑膜炎。这种抗生素在血脑屏障的穿透性较差，使其不适用于脑膜炎的治疗。如果头孢噻吩用于其他严重感染，应密切观察患者是否发生脑膜炎。
