Biology Department, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Curr Biol. 2013 Oct 7;23(19):R875-8. doi: 10.1016/j.cub.2013.08.049.
Localization of the histone H3 variant Cse4 (CENP-A) at the ~125 base pair point centromere in budding yeast directs assembly of a kinetochore that binds one microtubule. Recent work suggests there is more Cse4 at point centromeres than originally thought.
在芽殖酵母中，组蛋白 H3 变体 Cse4（着丝粒蛋白 A，CENP-A）定位于约 125 碱基对的着丝粒点，指导组装与一个微管结合的动粒。最近的研究表明，点着丝粒处的 Cse4 比最初认为的要多。
