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本文引用的文献

1
Lung cancer incidence and mortality in China, 2009.2009年中国肺癌的发病率与死亡率
Thorac Cancer. 2013 May;4(2):102-108. doi: 10.1111/1759-7714.12025.
2
Attributable causes of lung cancer incidence and mortality in China.中国肺癌发病率和死亡率的归因原因。
Thorac Cancer. 2011 Nov;2(4):156-163. doi: 10.1111/j.1759-7714.2011.00067.x.
3
Screening for lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.肺癌筛查：肺癌的诊断与管理，第 3 版：美国胸科医师学会循证临床实践指南。
Chest. 2013 May;143(5 Suppl):e78S-e92S. doi: 10.1378/chest.12-2350.
4
Annual number of lung cancer deaths potentially avertable by screening in the United States.美国通过筛查可避免的肺癌死亡人数。
Cancer. 2013 Apr 1;119(7):1381-5. doi: 10.1002/cncr.27813. Epub 2013 Feb 25.
5
Selection criteria for lung-cancer screening.肺癌筛查的选择标准。
N Engl J Med. 2013 Feb 21;368(8):728-36. doi: 10.1056/NEJMoa1211776.
6
Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial.计算机断层扫描筛查在随机 NELSON 试验中检测到的肺癌特征。
Am J Respir Crit Care Med. 2013 Apr 15;187(8):848-54. doi: 10.1164/rccm.201209-1651OC.
7
American Cancer Society lung cancer screening guidelines.美国癌症协会肺癌筛查指南。
CA Cancer J Clin. 2013 Mar-Apr;63(2):107-17. doi: 10.3322/caac.21172. Epub 2013 Jan 11.
8
Screening for lung cancer: Who should be screened?肺癌筛查：哪些人应该进行筛查？
Arch Pathol Lab Med. 2012 Dec;136(12):1511-4. doi: 10.5858/arpa.2012-0259-RA.
9
The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups.美国胸外科学会使用低剂量计算机断层扫描对肺癌幸存者和其他高危人群进行肺癌筛查的指南。
J Thorac Cardiovasc Surg. 2012 Jul;144(1):33-8. doi: 10.1016/j.jtcvs.2012.05.060.
10
Benefits and harms of CT screening for lung cancer: a systematic review.CT 筛查肺癌的获益与危害：系统评价。
JAMA. 2012 Jun 13;307(22):2418-29. doi: 10.1001/jama.2012.5521.

[低剂量螺旋CT肺癌筛查的进展]

[Advance of lung cancer screening with low-dose spiral CT].

作者信息

Ren Guanhua, Fan Yaguang, Zhao Yongcheng, Zhou Qinghua

机构信息

Peking Union Medical College & Institute of radiation medicine, Chinese Academy of Medical Science, Tianjin 300192, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2013 Oct 20;16(10):553-8. doi: 10.3779/j.issn.1009-3419.2013.10.10.

DOI:10.3779/j.issn.1009-3419.2013.10.10
PMID:24113010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6015170/
Abstract

Lung cancer has become the leading cause of cancer mortality globally, and 5-year survival rate is very poor. Screening and early detection are vital to improve survival and decrease mortality of lung cancer. In recent 20 years, low-dose spiral CT (LDCT) screening has become a research focus in this area. Randomized controlled trials have confirmed that LDCT can decrease lung cancer mortality. However, there are still some problems of LDCT. In this paper, we summarized the controversy that whether low-dose helical CT screening can reduce lung cancer mortality or not before its effectiveness was been confirmed, the results and problems in the randomized controlled trials and gave a prospect of low-dose helical CT screening's future application.

摘要

肺癌已成为全球癌症死亡的主要原因，其5年生存率很低。筛查和早期发现对于提高肺癌生存率和降低死亡率至关重要。近20年来，低剂量螺旋CT（LDCT）筛查已成为该领域的研究热点。随机对照试验已证实LDCT可降低肺癌死亡率。然而，LDCT仍存在一些问题。本文总结了在低剂量螺旋CT筛查有效性得到证实之前，其能否降低肺癌死亡率的争议、随机对照试验的结果及问题，并对低剂量螺旋CT筛查的未来应用进行了展望。