Seyal M, Gabor A J
Electroencephalogr Clin Neurophysiol. 1985 Sep;62(5):323-31. doi: 10.1016/0168-5597(85)90040-1.
Evidence has been obtained for the existence of two separate events occurring in the human spinal cord following posterior tibial nerve (PTN) stimulation. These events can be recorded on the surface in unanesthetized individuals. The first is an ascending wave which is conducted up to the cord at constant velocity and has a relatively short refractory period consistent with a compound nerve action potential. This represents the afferent volley traversing the lumbosacral plexus and the ascending dorsal columns. A second event, the N22/P22 complex, is surface negative on the back and surface positive anteriorly; its amplitude is maximal 5-15 cm above the level of the L4 spine and its peak latency remains constant at all levels. This activity has a relatively long refractory period. These characteristics of N22/P22 indicate that it is a localized synaptically dependent event conforming to a transverse dipole with dorsal negativity and a simultaneous anterior positivity. The N22/P22 is probably generated in the dorsal grey at the root entry zone. The N22/P22 is analogous to the stationary N13/P13 recorded over the neck following median nerve stimulation.
有证据表明，在刺激胫后神经（PTN）后，人类脊髓中会发生两个独立的事件。这些事件可以在未麻醉个体的体表记录到。第一个是上行波，它以恒定速度传导至脊髓，具有相对较短的不应期，这与复合神经动作电位一致。这代表传入冲动穿过腰骶丛和上行的背柱。第二个事件是N22/P22复合体，其在背部体表为负，在前部体表为正；其振幅在L4椎体水平上方5 - 15厘米处最大，其峰值潜伏期在所有水平均保持恒定。这种活动具有相对较长的不应期。N22/P22的这些特征表明它是一个局部的突触依赖性事件，符合具有背侧负性和同时前部正性的横向偶极子。N22/P22可能在神经根进入区的背侧灰质中产生。N22/P22类似于在正中神经刺激后在颈部记录到的静止N13/P13。
