Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Vic., Australia; Child Health Research Unit, Barwon Health, Geelong, Vic., Australia; University of Melbourne, Parkville, Vic., Australia.
Acta Paediatr. 2014 Feb;103(2):124-30. doi: 10.1111/apa.12457. Epub 2013 Dec 16.
Atherosclerosis is a chronic inflammatory process that begins in early life. Improved identification of markers of early atherosclerosis via neonatal aortic intima-media thickness (aIMT) measurement may allow the development of interventions to prevent or reduce later cardiovascular disease.
Using aIMT, studies have shown that antenatal factors such as intra-uterine growth retardation, prematurity, maternal factors and inflammation are associated with early cardiovascular changes.
动脉粥样硬化是一种始于生命早期的慢性炎症过程。通过测量新生儿主动脉内膜-中膜厚度（aIMT）来更好地识别早期动脉粥样硬化的标志物，可能有助于开发预防或减少日后心血管疾病的干预措施。
使用 aIMT，研究表明，宫内发育迟缓、早产、母体因素和炎症等产前因素与早期心血管变化有关。
