Department of Mechanical Engineering, Biomechanics Lab, McGill University, Montreal, Quebec, Canada.
J Voice. 2013 Nov;27(6):769-77. doi: 10.1016/j.jvoice.2013.06.003. Epub 2013 Oct 8.
Three-dimensional (3D) computer models of the human larynx are useful tools for research and for eventual clinical applications. Recently, computed tomography (CT) scanning and magnetic resonance imaging (MRI) have been used to recreate realistic models of human larynx. In the present study, CT images were used to create computer models of vocal folds, vocal tract, and laryngeal cartilages, and the procedure to create solid models are explained in details. Vocal fold and vocal tract 3D models of healthy and postsurgery larynges during phonation and respiration were created and morphometric parameters were quantified. The laryngeal framework of eight patients was also reconstructed from CT scan images. For each cartilage, morphometric landmarks were measured on the basis of their importance for biomechanical modeling. A quantitative comparison was made between measured values from the reconstructions and those from human excised larynges in literature. The good agreement between these measurements supports the accuracy of CT scan-based 3D models. Generic standard models of the laryngeal framework were created using known features in modeling softwares. They were created based on the morphometric landmark dimensions previously defined, preserving all biomechanically important dimensions. These models are accessible, subject independent, easy to use for computational simulations, and make the comparisons between different studies possible.
三维（3D）计算机模型是研究和最终临床应用的有用工具。最近，计算机断层扫描（CT）和磁共振成像（MRI）已被用于重建真实的人类喉模型。在本研究中，使用 CT 图像创建了声带、声道和喉软骨的计算机模型，并详细解释了创建实体模型的过程。创建了发声和呼吸时健康和手术后喉部的声带和声道 3D 模型，并量化了形态参数。还根据对生物力学建模的重要性，从 CT 扫描图像重建了 8 名患者的喉框架。针对每个软骨，在其基础上测量形态学标志点，用于生物力学建模。对重建测量值和文献中人体切除喉的测量值进行了定量比较。这些测量值之间的良好一致性支持基于 CT 扫描的 3D 模型的准确性。使用建模软件中的已知特征创建了通用标准喉框架模型。它们是根据先前定义的形态学标志点尺寸创建的，保留了所有具有生物力学重要性的尺寸。这些模型可访问、与个体无关、易于用于计算模拟，并可实现不同研究之间的比较。
