Willdeck-Lund G, Edström H
Acta Anaesthesiol Scand Suppl. 1975;60:33-8. doi: 10.1111/j.1399-6576.1975.tb05403.x.
For pain relief after thoracotomy, intercostal nerve block with etidocaine 1% and bupivacaine 0.5%, both containing adrenaline 5 mug/ml, was used. Duration of skin analgesia for sharp pain was around 11 hours for both solutions. Post-operative pain was noted 6 and 5 hours after injection for etidocaine and bupivacaine respectively. No pathological changes in acid-base balance or ventilation were observed. Peak expiratory flow decreased to 35-40% of the pre-operative values and remained at this level for about 12 hours. Arterial and venous blood levels of the local anaesthetics were low and no signs of toxicity were noted. All patients experienced a certain pain relief from the blocks. Because of shoulder pain in some patients intercostal nerve block alone does not seem to be a perfect post-operative method for pain relief after thoracotomies.
为缓解开胸术后疼痛，使用了含5μg/ml肾上腺素的1%依替卡因和0.5%布比卡因进行肋间神经阻滞。两种溶液对锐痛的皮肤镇痛持续时间约为11小时。依替卡因和布比卡因注射后分别在6小时和5小时出现术后疼痛。未观察到酸碱平衡或通气的病理变化。呼气峰值流量降至术前值的35%-40%，并在该水平维持约12小时。局部麻醉药的动脉和静脉血水平较低，未观察到毒性迹象。所有患者均从阻滞中获得了一定程度的疼痛缓解。由于部分患者出现肩部疼痛，单独的肋间神经阻滞似乎并非开胸术后疼痛缓解的理想术后方法。
