Radtke H, Nolte H, Fruhstorfer H, Zenz M
Acta Anaesthesiol Scand Suppl. 1975;60:17-20. doi: 10.1111/j.1399-6576.1975.tb05399.x.
The long-acting local anaesthetics bupivacaine and etidocaine were compared in a double-blind study using ulnar nerve block. Eleven volunteers took part in the study. Solutions used were: bupivacaine 0.25% and 0.5% and etidocaine 0.5% and 1 %. All solutions contained adrenaline 5 mug/ml. The time of onset and duration of analgesia and motor block, degree of motor block, and changes in skin temperature were investigated. The results did not show any differences in the duration of sensory of motor block. Differences were seen in the degree of motor block in favour of etidocaine. The sympathetic block seemed to be more intense and of longer duration with bupivacaine. Etidocaine had a shorter time of onset in all nerve fibres.
在一项使用尺神经阻滞的双盲研究中，对长效局麻药布比卡因和依替卡因进行了比较。11名志愿者参与了该研究。使用的溶液有：0.25%和0.5%的布比卡因以及0.5%和1%的依替卡因。所有溶液均含有5μg/ml肾上腺素。研究了镇痛和运动阻滞的起效时间、持续时间、运动阻滞程度以及皮肤温度变化。结果显示感觉或运动阻滞的持续时间没有差异。在运动阻滞程度上存在差异，依替卡因更具优势。布比卡因引起的交感神经阻滞似乎更强且持续时间更长。依替卡因在所有神经纤维中的起效时间更短。
