School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China.
J Chromatogr A. 2013 Nov 5;1316:127-34. doi: 10.1016/j.chroma.2013.09.077. Epub 2013 Sep 27.
This report describes the development and application of a novel graphene-epoxy composite electrode as a sensitive amperometric detector of capillary electrophoresis. The composite electrode was fabricated on the basis of the in situ polycondensation of a mixture of graphene and 1,2-ethanediamine-containing bisphenol A epoxy resin in the inner bore of a piece of fused silica capillary under heat. The structure of the material was investigated by scanning electron microscopy, thermogravimetric analysis, X-ray diffraction, and Fourier transform infrared spectroscopy. The results indicated that graphene sheets were well dispersed and interconnected throughout the composite to form an electrically conductive network. The performance of this unique electrode was demonstrated by separating and detecting two naturally occurring phenolic compounds in rosemary in combination with capillary electrophoresis. The graphene-based detector offered significantly lower operating potentials, higher sensitivity, satisfactory resistance to surface fouling, and lower expense of operation, indicating great promise for a wide range of applications.
本报告描述了一种新型石墨烯-环氧树脂复合电极的开发和应用，该电极作为毛细管电泳的灵敏安培检测。该复合电极是基于石墨烯和含有 1,2-乙二胺的双酚 A 环氧树脂混合物在热作用下原位聚缩合在一段熔融石英毛细管内孔中制备的。通过扫描电子显微镜、热重分析、X 射线衍射和傅里叶变换红外光谱对材料的结构进行了研究。结果表明，石墨烯片在整个复合材料中很好地分散和相互连接，形成了一个导电网络。通过与毛细管电泳相结合，从迷迭香中分离和检测两种天然酚类化合物，证明了这种独特电极的性能。基于石墨烯的检测器具有更低的工作电位、更高的灵敏度、对表面污染的良好抵抗力和更低的操作成本，这表明它在广泛的应用中具有很大的潜力。
