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动物实验中血压调节药物与眼压(作者译)

[Blood-pressure regulating drugs and intraocular pressure in animal experiments (author's transl)].

作者信息

Genée E, Geissendörfer T

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Jun 6;195(3):187-94. doi: 10.1007/BF00410470.

DOI:10.1007/BF00410470
PMID:241263
Abstract

Electromanometric measurements of blood pressure and intraocular pressure, carried out in rabbits after the intravenous administration of Norphen, Peripherin, Sympatol, Hydergin, Tropodil, Complamin, Euphyllin and Vasculat showed that the changes in the pressure curves were largely in the same sense. Apart from a "passive" correlation of the intraocular pressure with the blood pressure, the local effects of pharmaceuticals administered are also discussed. The results obtained provide both general medicine and ophthalmology with insights into the mode of action of drugs, some of which are frequently administered. In addition, they serve both to provide information on the desirable curative effects of the drugs and to help prevent damage being done to the organ of sight.

摘要

在给兔子静脉注射去甲麻黄碱、外周蛋白、交感酚、喜得镇、托哌碘铵、康普明、氨茶碱和血管舒张素后进行的血压和眼压电子测压测量表明,压力曲线的变化在很大程度上是相同的。除了眼压与血压的“被动”相关性外,还讨论了所给药的局部作用。所获得的结果为普通医学和眼科提供了对某些常用药物作用方式的见解。此外,它们既有助于提供有关药物预期疗效的信息,又有助于防止对视器官造成损害。

相似文献

1
[Blood-pressure regulating drugs and intraocular pressure in animal experiments (author's transl)].动物实验中血压调节药物与眼压(作者译)
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Jun 6;195(3):187-94. doi: 10.1007/BF00410470.
2
[The influence of vasodilatators on intraocular pressure and blood pressure (author's transl)].
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 May 23;202(3):213-22. doi: 10.1007/BF00407871.
3
Pharmacological evaluation of xanthinol nicotinate (complamin).烟酸占替诺(脑脉康)的药理学评价
J Egypt Med Assoc. 1976;59(1-2):141-9.
4
[Elucidation of the mechanism of nicotinic acid flush in the animal experiment (author's transl)].
Arzneimittelforschung. 1977;27(12):2347-52.
5
[Effect of acetylsalicyclic and nicotinic acids and complamin on the formation of a prostacyclin-like substance by the aortic wall].
Farmakol Toksikol. 1980 Sep-Oct;43(5):581-5.
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Nippon Ganka Gakkai Zasshi. 1980 Oct 10;84(10):1450-2.
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[The effect of the beta1-24 corticotropic hormone, angiotensin II and xanthinol nicotinate on the kinetics of aldosterone (author's transl)].
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The influence of drugs on the electro-oculogram.药物对眼电图的影响。
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引用本文的文献

1
A comparative study of topical natural ergot alkaloids on the intraocular pressure and aqueous humor dynamics in oclular normotensive and alpha-chymotrypsin-induced ocular hypertensive rabbits.局部应用天然麦角生物碱对正常眼压和α-糜蛋白酶诱导的高眼压兔眼压及房水动力学的比较研究
Graefes Arch Clin Exp Ophthalmol. 2007 Oct;245(10):1559-67. doi: 10.1007/s00417-007-0596-3. Epub 2007 May 16.
2
[The influence of vasodilatators on intraocular pressure and blood pressure (author's transl)].
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 May 23;202(3):213-22. doi: 10.1007/BF00407871.

本文引用的文献

1
[The influence of theophylline derivatives and their combinations on cerebral blood flow].[茶碱衍生物及其组合对脑血流量的影响]
Arzneimittelforschung. 1958 Aug;8(8):503-7.
2
[Changes of blood pressure and eye pressure in weight lifting].[举重过程中血压和眼压的变化]
Klin Monbl Augenheilkd. 1965;147(6):827-33.
3
[Treatment of symptoms of premature deterioration after head-brain injuries. Experience with tropodil].[颅脑损伤后过早恶化症状的治疗。曲吡那敏的应用经验]
Munch Med Wochenschr. 1968 Nov 29;110(48):2827-9.
4
[Clinical experience with Complamine in vascular diseases of the fundus oculi].[Complamine治疗眼底血管疾病的临床经验]
Klin Monbl Augenheilkd. 1967;151(2):201-7.
5
[The relationship between blood pressure, blood circulation, osmotic pressure and intraocular pressure].[血压、血液循环、渗透压与眼压之间的关系]
Ber Zusammenkunft Dtsch Ophthalmol Ges. 1970;70:493-9.
6
[Observations and analyses of microcirculatory processes of the rat eye. II. On the pharmacological influenceability of the iris vascular system].
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1967;172(4):326-45. doi: 10.1007/BF02384793.