Mackillop W J, Pringle J F
Cancer. 1985 Nov 15;56(10):2519-23. doi: 10.1002/1097-0142(19851115)56:10<2519::aid-cncr2820561033>3.0.co;2-m.
The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10-year period at the Princess Margaret Hospital, Toronto. Overall 5-year survival was 45.5% and disease-free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distribution of disease, the presence of symptoms other than vaginal bleeding or discharge, and completeness of surgery. Isolated involvement of the ovary or fallopian tube emerges as a distinct syndrome with a good prognosis (5-year survival of 82.3%). Surgery is the treatment of choice for operable cases, but 13 of 36 patients with inoperable disease who completed radical radiotherapy were alive and free of disease at 5 years.
作者对多伦多玛格丽特公主医院10年间收治的90例Ⅲ期子宫内膜癌患者进行了回顾性研究。总体5年生存率为45.5%，无病生存率为36.0%。Ⅲ期患者的预后因素包括肿瘤分级、疾病的地理分布、除阴道出血或排液以外的症状以及手术的完整性。卵巢或输卵管孤立受累表现为一种预后良好的独特综合征（5年生存率为82.3%）。手术是可手术病例的首选治疗方法，但36例无法手术的患者中有13例在完成根治性放疗后5年仍存活且无疾病。
