Solov'ev V N, Borodin Iu P, Berezina E K, Kovalenko L P
Antibiotiki. 1975 Sep(9):846-53.
Immunization of Syrian female hamsters with benzylpenicillin and ampicillin resulted in positive skin reactions of the retarded type and decreased titers of the blood antihistamine factor (AHF) in a part of the posterity. Penicillin allergy was in particular observed in the posterity of the female hamsters immunited before the pregnancy. The state of allergy to penicillins was found in the posterity of the female hamsters with both the positive and negative skin reactions on immunization during the 2nd half of the pregnancy.
用苄青霉素和氨苄青霉素对叙利亚雌性仓鼠进行免疫接种，导致迟发型皮肤阳性反应，并使一部分后代血液中抗组胺因子（AHF）滴度降低。尤其在怀孕前接受免疫接种的雌性仓鼠的后代中观察到青霉素过敏。在怀孕后半期免疫接种时皮肤反应呈阳性和阴性的雌性仓鼠的后代中均发现了对青霉素的过敏状态。
